Primary non-Hodgkin’s lymphoma of the breast treated nonsurgically: report of three cases

Extranodal non-Hodgkin’s lymphoma (NHL) is a rare breast disease. Here we report three cases of primary NHL of the breast. The first patient was a 29-year-old woman with a firm mass in her right breast with ipsilateral axillary lymphadenopathy. An excisional biopsy revealed NHLs. Clinical stage was...

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Bibliographic Details
Published in:Breast cancer (Tokyo, Japan) Japan), 2011, Vol.18 (1), p.68-72
Main Authors: Ogawa, Toshihisa, Tsuji, Ei-ichi, Shirakawa, Kazuo, Hayashibara, Noriaki, Kurabayashi, Rie, Terada, Kotoe, Kikuchi, Yasuko, Kanauchi, Hajime, Sakatani, Takashi
Format: Article
Language:English
Subjects:
Adult
Aged
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Breast Neoplasms - pathology
Breast Neoplasms - therapy
Cancer
Cancer Research
Care and treatment
Case Report
Chemotherapy
Combined Modality Therapy
Female
Humans
Lymphoma, Non-Hodgkin - pathology
Lymphoma, Non-Hodgkin - therapy
Medical colleges
Medicine
Medicine & Public Health
Non-Hodgkin's lymphomas
Oncology
Radiotherapy Dosage
Surgery
Surgical Oncology
Treatment Outcome
Vincristine
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Summary:Extranodal non-Hodgkin’s lymphoma (NHL) is a rare breast disease. Here we report three cases of primary NHL of the breast. The first patient was a 29-year-old woman with a firm mass in her right breast with ipsilateral axillary lymphadenopathy. An excisional biopsy revealed NHLs. Clinical stage was IIAE. The tumor and enlarged lymph nodes had successfully been treated following the combination therapy. The second patient was a 70-year-old women with an elastic hard mass in her left breast. An excisional biopsy revealed NHLs and clinical stage was 1AE. The tumor disappeared following the combination therapy. The third patient was a 67-year-old women with a hard mass in her left breast. Core needle biopsy revealed NHLs and clinical stage was 1AE. The tumor disappeared following chemotherapy. All patients are alive with no evidence of recurrence 4–8 years after the initial treatment. Although a standard treatment has yet to be established, an initial treatment with combination therapy without surgical intervention including axillary dissection appears to be appropriate for this rare disease.
ISSN:1340-6868
1880-4233
DOI:10.1007/s12282-009-0107-y