The determination of aspirin levels in the presence of hyperbilirubinemia

Many major medical centers are presently utilizing a shortened method (Keller) for determining serum aspirin levels which does not remove interfering compounds. This report documents that the presence of even 1 mg of bilirubin/dl of serum is sufficient to cause a falsely high aspirin level. It is su...

Full description

Saved in:
Bibliographic Details
Published in:Pediatrics (Evanston) 1977-01, Vol.59 (1), p.55-57
Main Authors: Fenton, L J, Beresford, M E, Keenan, W J
Format: Article
Language:English
Subjects:
Aspirin - blood
Blood Chemical Analysis - methods
False Positive Reactions
Female
Humans
Infant, Newborn
Jaundice, Neonatal - blood
Maternal-Fetal Exchange
Methods
Pregnancy
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Many major medical centers are presently utilizing a shortened method (Keller) for determining serum aspirin levels which does not remove interfering compounds. This report documents that the presence of even 1 mg of bilirubin/dl of serum is sufficient to cause a falsely high aspirin level. It is suggested that any method for determining serum bilirubin which does not remove interfering substances constitutes a danger to many groups of patients and should be discontinued.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.59.1.55