A cancer-associated, fast, homoarginine-sensitive electrophoretic form of serum alkaline phosphatase

Serum from patients with a variety of cancers often (p = 70%) contains a characteristic electrophoretic form of alkaline phosphatase detectable by cellulose polyacetate electrophoresis. The lower prevalence of this electrophoretic form in presumably healthy individuals (p = 7%) and noncancer hospita...

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Bibliographic Details
Published in:Cancer research (Chicago, Ill.) Ill.), 1978-03, Vol.38 (3), p.599-601
Main Authors: Ehrmeyer, S L, Joiner, B L, Kahan, L, Larson, F C, Metzenberg, R L
Format: Article
Language:English
Subjects:
Adult
Alkaline Phosphatase - blood
Alkaline Phosphatase - isolation & purification
Arginine - analogs & derivatives
Electrophoresis, Cellulose Acetate
Female
Homoarginine - pharmacology
Humans
Isoenzymes - blood
Male
Neoplasms - enzymology
Remission, Spontaneous
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Summary:Serum from patients with a variety of cancers often (p = 70%) contains a characteristic electrophoretic form of alkaline phosphatase detectable by cellulose polyacetate electrophoresis. The lower prevalence of this electrophoretic form in presumably healthy individuals (p = 7%) and noncancer hospitalized patients (p = 30%) suggests that it may be useful as a diagnostic or monitory marker.
ISSN:0008-5472