An Antigenic Subunit Present in Rotavirus Infected Faeces

Department of Pathology, Christian Medical College and Hospital, Vellore June D. Almeida and Janet Cole Wellcome Research Laboratories, Beckenham, Kent It has been found by immune electron microscopy that rotavirus-infected faeces, calf or human, contain an antigenic subunit associated with the inne...

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Bibliographic Details
Published in:Journal of general virology 1977-02, Vol.34 (2), p.325-329
Main Authors: Mathan, Minnie, Almeida, June D, Cole, Janet
Format: Article
Language:English
Subjects:
Animals
Antigens, Viral - analysis
Capsid - immunology
Cattle
Epitopes
Feces - microbiology
Humans
Immunodiffusion
Microscopy, Electron
Reoviridae - immunology
RNA Viruses - immunology
RNA Viruses - ultrastructure
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Summary:Department of Pathology, Christian Medical College and Hospital, Vellore June D. Almeida and Janet Cole Wellcome Research Laboratories, Beckenham, Kent It has been found by immune electron microscopy that rotavirus-infected faeces, calf or human, contain an antigenic subunit associated with the inner of the two virus capsids. This internal component represents the group specific antigen for the rotavirus group and the subunit reacts with both homologous and heterologous antiserum. It can therefore be used in diagnostic tests and in this paper its use as a reagent for immunodiffusion is described. Received 7 September 1976; accepted 15 September 1976.
ISSN:0022-1317
1465-2099
DOI:10.1099/0022-1317-34-2-325