Proximal tubulare dysfunction associated with Burkitt's lymphoma

Generalized aminoaciduria, uricosuria, glycosuria and phosphaturia were discovered in a patient with advanced Burkitt's lymphoma with renal infiltration. The literature is reviewed and three pathogenetic mechanisms are discussed. It is presumed that proximal tubular dysfunction in this case was...

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Bibliographic Details
Published in:Cancer 1978-02, Vol.41 (2), p.568-577
Main Authors: Goldsweig, H G, Brisson de Champlain, M L, Davidman, M
Format: Article
Language:English
Subjects:
Adult
Aged
Autoantibodies
Basement Membrane - immunology
Fanconi Syndrome - complications
Fanconi Syndrome - etiology
Fanconi Syndrome - pathology
Female
Hodgkin Disease - complications
Hodgkin Disease - pathology
Humans
Kidney - pathology
Kidney Tubules, Proximal - immunology
Male
Middle Aged
Neoplasm Invasiveness
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Summary:Generalized aminoaciduria, uricosuria, glycosuria and phosphaturia were discovered in a patient with advanced Burkitt's lymphoma with renal infiltration. The literature is reviewed and three pathogenetic mechanisms are discussed. It is presumed that proximal tubular dysfunction in this case was related to the marked peritubular infiltrate causing cell mediated immunological injury or direct tubular destruction by tumor.
ISSN:0008-543X