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Pathogenic mycoplasmas: cultivation and vertebrate pathogenicity of a new spiroplasma

A spiroplasma recovered from allantoic fluids of chick embryos infected with the tick-derived suckling mouse cataract agent was grown in continuous passage on a new artificial culture medium. The cultured organisms induced typical ocular and other disease symptoms in susceptible animals, and were re...

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Published in:	Science (American Association for the Advancement of Science) 1977-03, Vol.195 (4281), p.892-894
Main Authors:	Tully, J.G, Whitcomb, R.F, Clark, H.F, Williamson, D.L
Format:	Article
Language:	English
Subjects:	animal diseases animal health Animals Antigens, Bacterial - analysis Arachnid Vectors Cataract - veterinary Fungiculture Mice Mycoplasma Mycoplasmatales Infections - microbiology Mycoplasmatales Infections - transmission Plant diseases Plants Rats Rodent Diseases - microbiology Spiroplasma Spiroplasma - immunology Spiroplasma - isolation & purification Spiroplasma - pathogenicity Suckling Ticks - microbiology Vertebrates
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container_end_page	894
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creator	Tully, J.G Whitcomb, R.F Clark, H.F Williamson, D.L
description	A spiroplasma recovered from allantoic fluids of chick embryos infected with the tick-derived suckling mouse cataract agent was grown in continuous passage on a new artificial culture medium. The cultured organisms induced typical ocular and other disease symptoms in susceptible animals, and were reisolated from involved host tissues. Although spiroplasmas have been previously recognized as plant and insect pathogens, this is the first spiroplasma shown to multiply at 37°C and to be pathogenic for vertebrates.
doi_str_mv	10.1126/science.841314
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identifier	ISSN: 0036-8075
ispartof	Science (American Association for the Advancement of Science), 1977-03, Vol.195 (4281), p.892-894
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subjects	animal diseases animal health Animals Antigens, Bacterial - analysis Arachnid Vectors Cataract - veterinary Fungiculture Mice Mycoplasma Mycoplasmatales Infections - microbiology Mycoplasmatales Infections - transmission Plant diseases Plants Rats Rodent Diseases - microbiology Spiroplasma Spiroplasma - immunology Spiroplasma - isolation & purification Spiroplasma - pathogenicity Suckling Ticks - microbiology Vertebrates
title	Pathogenic mycoplasmas: cultivation and vertebrate pathogenicity of a new spiroplasma
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