A biochemical and electron microscopy study of rice bodies from rheumatoid patients

Rice bodies (corpora oryzoidea) from rheumatoid patients were studied biochemically and by electron microscopy. The data indicate that only a relatively small portion of the rice bodies is identical to fibrin, and the bulk is composed of other fibrinlike mucoproteins and a small amount of lipids. So...

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Bibliographic Details
Published in:Arthritis and rheumatism 1965-12, Vol.8 (6), p.1053-1063
Main Authors: Albrecht, Manfred, Marinetti, Guido V., Jacox, Ralph F., Vaughan, John H.
Format: Article
Language:English
Subjects:
Arthritis, Rheumatoid
Chemistry Techniques, Analytical
Fibrin
Humans
Joint Diseases
Microscopy, Electron
Mucoproteins
Synovial Fluid
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Summary:Rice bodies (corpora oryzoidea) from rheumatoid patients were studied biochemically and by electron microscopy. The data indicate that only a relatively small portion of the rice bodies is identical to fibrin, and the bulk is composed of other fibrinlike mucoproteins and a small amount of lipids. Some lipids and neuraminic acid are located on the surface. The recurrence of rice bodies is prevented by synovectomy. Fibrous rice bodies represent an end product of synovial inflammation, proliferation, and subsequent secondary degeneration. Corpores oryzoidee ab patientes rheumatoide esseva studiate biochimicamente e per microscopia electronic. Le datos indica que solo un relativemente micre portion del corpores oryzoidee es identic con fibrina durante que le plus grande portion de illos es componite de altere mucoproteinas fibrinoide e de un micre quantitate de lipido. Un certe quantitate de lipido e de acido neuraminic es locate al superficie. Le recurrentia de corpores oryzoide es prevenite per synoviectomia. Fibrotic corpores oryzoide representa un producto final de inflammation, proliferation, e subsequente degeneration secundari synovial.
ISSN:0004-3591
1529-0131
DOI:10.1002/art.1780080605