THE EFFECT OF ANGIOCARDIOGRAPHIC CONTRAST MEDIUM ON CIRCULATORY DYNAMICS IN MAN. CARDIAC OUTPUT DURING ANGIOCARDIOGRAPHY

The cardiovascular response to angiographic contrast medium was studied in 28 patients undergoing diagnostic angiocardiography under anesthesia. A transient phase of hypotension and tachycardia similar to that described by other authors was noted. Cardiac output was increased initially by 50 per cen...

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Bibliographic Details
Published in:Circulation (New York, N.Y.) N.Y.), 1965-02, Vol.31 (2), p.234-240
Main Authors: BROWN, R, RAHIMTOOLA, S H, DAVIS, G D, SWAN, H J
Format: Article
Language:English
Subjects:
Angiocardiography
Aortic Coarctation
Aortic Valve Stenosis
Blood Circulation
Blood Volume
Cardiac Catheterization
Cardiac Output
Contrast Media
Dextrans
Dye Dilution Technique
Heart
Heart Septal Defects
Heart Septal Defects, Atrial
Heart Valve Diseases
Humans
Male
Muscles
Old Medline
Pharmacology
Physiology
Pulmonary Valve Stenosis
Tetralogy of Fallot
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Summary:The cardiovascular response to angiographic contrast medium was studied in 28 patients undergoing diagnostic angiocardiography under anesthesia. A transient phase of hypotension and tachycardia similar to that described by other authors was noted. Cardiac output was increased initially by 50 per cent and returned to the base line in 20 minutes. Peripheral blood flow increased by 100 per cent, apparently due to the direct effect of the hyperosmotic solution on the vascular smooth muscle. Hemodilution, maximal 2 to 4 minutes after injection of contrast medium, suggested a transient increase in circulating blood volume. Increased ventricular filling pressures, which were thought to be due to hypervolemia, were associated with increased left ventricular stroke work.
ISSN:0009-7322
1524-4539
DOI:10.1161/01.CIR.31.2.234