Relative pathogenicity ofCandida tropicalis in rat tongue mucosa

The potential ofC. tropicalis to colonize and infect rat tongue mucosa was demonstrated. Thirty female Sprague-Dawley rats were infected orally with three different strains ofC. tropicalis. The animals were killed one and three weeks following the inoculation and sections of their tongue were staine...

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Bibliographic Details
Published in:Folia microbiologica 2000-12, Vol.45 (6), p.561-565
Main Authors: Dorko, E., Pilipčinec, E., Bračoková, I., Jenča, A., Švicky, E., Danko, J., Tkáčiková, L., Dorko, F., Kočišová, M., Lovásova, K.
Format: Article
Language:English
Subjects:
Abscesses
Animals
Diabetes mellitus
Epithelium
Hyphae
Immunization
Inoculation
Mucosa
Myositis
Pathogenicity
Pathogens
Rodents
Tongue
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Summary:The potential ofC. tropicalis to colonize and infect rat tongue mucosa was demonstrated. Thirty female Sprague-Dawley rats were infected orally with three different strains ofC. tropicalis. The animals were killed one and three weeks following the inoculation and sections of their tongue were stained with hematoxylin-eosin and Grocott stain. Histological changes were observed in the group of animals killed one week after inoculation and infected withC. tropicalis strain isolated from the crural ulcer of a diabetic patient. The most important finding was acute purulent myositis with the formation of abscesses. The myositis was local without signs of spreading to the surrounding tissue. Epithelium-penetrating hyphae observed in the Grocott-stained sections were relatively fewer and more sparsely distributed.
ISSN:0015-5632
1874-9356
DOI:10.1007/BF02818727