Sensitivity of various human lymphoblastoid cells to the antiviral and anticellular activity of human leukocyte interferon

Of eight lymphoblastoid cell lines studied five were insensitive to both the anticellular and antiviral activities of human leukocyte interferon, and two were sensitive to both activities. One line could not be fully evaluated since it was not possible to study its sensitivity to the antiviral activ...

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Bibliographic Details
Published in:Archives of virology 1977-09, Vol.54 (3), p.271-277
Main Authors: Hilfenhaus, J, Damm, H, Johannsen, R
Format: Article
Language:English
Subjects:
Animals
Burkitt Lymphoma
Callitrichinae
Cell Division - drug effects
Cell Line
Cell Transformation, Neoplastic
Cells, Cultured - drug effects
Haplorhini
Humans
Infectious Mononucleosis
Interferons - biosynthesis
Interferons - pharmacology
Leukemia
Leukemia, Lymphoid
Leukocytes - metabolism
Semliki forest virus - drug effects
Semliki forest virus - growth & development
Virus Replication - drug effects
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Description
Summary:Of eight lymphoblastoid cell lines studied five were insensitive to both the anticellular and antiviral activities of human leukocyte interferon, and two were sensitive to both activities. One line could not be fully evaluated since it was not possible to study its sensitivity to the antiviral activity.
ISSN:0304-8608
1432-8798
DOI:10.1007/BF01314795