Purification and properties of four biologically active components of whale luteinizing hormone

Four biologically active components of luteinizing hormone (LH), designated as LH I, H, III, and IV, were isolated from whale pituitary glands. These components migrated as single bands with different mobilities in disc electrophoresis, and their isoelectric points were at pH 8.1, 8.3, 8.5, and 8.7,...

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Bibliographic Details
Published in:Journal of biochemistry (Tokyo) 1977-04, Vol.81 (4), p.1155-1160
Main Authors: TAMURA-TAKAHASHI, Hiroko, UI, Nobuo
Format: Article
Language:English
Subjects:
Amino Acids - analysis
Animals
Carbohydrates - analysis
Cetacea
Chromatography, Gel
Luteinizing Hormone - isolation & purification
Molecular Weight
Pituitary Gland - analysis
Species Specificity
Whales
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Description
Summary:Four biologically active components of luteinizing hormone (LH), designated as LH I, H, III, and IV, were isolated from whale pituitary glands. These components migrated as single bands with different mobilities in disc electrophoresis, and their isoelectric points were at pH 8.1, 8.3, 8.5, and 8.7, respectively. Their amino acid and carbohydrate compositions showed close similarity. The molecular weight of whale LH was determined to be 31,000 by sedimentation equilibrium, and no difference was detected among the four components. The molecular properties of whale LH were compared with the previously reported data for LH from other animal species.
ISSN:0021-924X
1756-2651
DOI:10.1093/oxfordjournals.jbchem.a131541