MACROLIDE ANTIBIOTICS M-4365 PRODUCED BY MICROMONOSPORA: II. CHEMICAL STRUCTURES

By physicochemical analyses and chemical procedures, the structures of a series of basic 16-membered macrolide antibiotics, M-4365 A1, A2, A3, G1, G2, and G3 were elucidated, and it was found that M-4365 A1, G1 and G2 were novel, while M-4365 A2, A3 and G3 were identical with rosamicin, juvenimicins...

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Bibliographic Details
Published in:Journal of antibiotics 1977, Vol.30(6), pp.450-454
Main Authors: KINUMAKI, AKIO, HARADA, KEN-ICHI, SUZUKI, TOSHIKAZU, SUZUKI, MAKOTO, OKUDA, TOMOHARU
Format: Article
Language:English
Subjects:
Aminoglycosides
Anti-Bacterial Agents - biosynthesis
Chemical Phenomena
Chemistry
Lactones
Magnetic Resonance Spectroscopy
Mass Spectrometry
Micromonospora - metabolism
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Summary:By physicochemical analyses and chemical procedures, the structures of a series of basic 16-membered macrolide antibiotics, M-4365 A1, A2, A3, G1, G2, and G3 were elucidated, and it was found that M-4365 A1, G1 and G2 were novel, while M-4365 A2, A3 and G3 were identical with rosamicin, juvenimicins A4 and B1, respectively.
ISSN:0021-8820
1881-1469
DOI:10.7164/antibiotics.30.450