Puromycin Effect on Successive Phases of Memory Storage
Mice injected bitemporally with puromycin 5 hours before training learned to escape or to avoid shock by choosing the correct limb of a Y-maze. When retested 15 minutes after training they had normal retention. In the ensuing 2$\frac{3}{4}$ hours the animals injected with puromycin, unlike the contr...
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Published in: | Science (American Association for the Advancement of Science) 1966-02, Vol.151 (3710), p.594-595 |
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Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Mice injected bitemporally with puromycin 5 hours before training learned to escape or to avoid shock by choosing the correct limb of a Y-maze. When retested 15 minutes after training they had normal retention. In the ensuing 2$\frac{3}{4}$ hours the animals injected with puromycin, unlike the controls, showed a progressive decrease of savings to less than 7 percent. |
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ISSN: | 0036-8075 1095-9203 |
DOI: | 10.1126/science.151.3710.594 |