Erythrocyte DPNH dependent diaphorase levels in infants

Infants during the first 4 months of life are reported to be more susceptible than older children and adults to the acquisition of methemoglobinemia, and premature neonates are more susceptible than full-term infants. Erythrocyte DPNH-dependent diaphorase is the major enzyme which catalyzes the redu...

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Published in:Pediatrics (Evanston) 1966-06, Vol.37 (6), p.991-993
Main Authors: Bartos, H R, Desforges, J F
Format: Article
Language:English
Subjects:
Dihydrolipoamide Dehydrogenase
Erythrocytes
Humans
Infant, Newborn
Methemoglobin
Methemoglobinemia
NAD
Spectrophotometry
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container_title Pediatrics (Evanston)
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creator Bartos, H R
Desforges, J F
description Infants during the first 4 months of life are reported to be more susceptible than older children and adults to the acquisition of methemoglobinemia, and premature neonates are more susceptible than full-term infants. Erythrocyte DPNH-dependent diaphorase is the major enzyme which catalyzes the reduction of methemoglobin to hemoglobin. The data presented show that during the period of infancy in which susceptibility to methemoglobinemia has been reported there is decreased diaphorase activity, and this is postulated to be a major factor in the pathogenesis of methemoglobinemia in infancy.
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source Free E-Journal (出版社公開部分のみ）
subjects Dihydrolipoamide Dehydrogenase
Erythrocytes
Humans
Infant, Newborn
Methemoglobin
Methemoglobinemia
NAD
Spectrophotometry
title Erythrocyte DPNH dependent diaphorase levels in infants
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