Loading…

Sleep: Suppression of Rapid Eye Movement Phase in the Cat after Electroconvulsive Shock

Electroconvulsive shock, administered for 5 to 7 days, reduced the daily rapid eye movement sleep time of seven cats to as little as 28 percent of base line levels. After day 4, eye movements during periods of cortical activation without tonic electromyographic activity were greatly reduced. Althoug...

Full description

Saved in:

Bibliographic Details
Published in:	Science (American Association for the Advancement of Science) 1966-10, Vol.154 (3747), p.396-398
Main Authors:	Cohen, Harry B., Dement, William C.
Format:	Article
Language:	English
Subjects:	Animals Cats Convulsions Electroconvulsive Therapy Ethyl Ethers - pharmacology Eye Movements Female Hemoglobins In rem Intravenous injections Male Pentylenetetrazole - pharmacology Phenotypes Rapid eye movement sleep Sleep Sleep deprivation
Citations:	Items that this one cites Items that cite this one
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by	cdi_FETCH-LOGICAL-c353t-eb7764beba7698fbb8008d2cc6fc1879bddc42bac2ed1409b8a31b908d956e193
cites	cdi_FETCH-LOGICAL-c353t-eb7764beba7698fbb8008d2cc6fc1879bddc42bac2ed1409b8a31b908d956e193
container_end_page	398
container_issue	3747
container_start_page	396
container_title	Science (American Association for the Advancement of Science)
container_volume	154
creator	Cohen, Harry B. Dement, William C.
description	Electroconvulsive shock, administered for 5 to 7 days, reduced the daily rapid eye movement sleep time of seven cats to as little as 28 percent of base line levels. After day 4, eye movements during periods of cortical activation without tonic electromyographic activity were greatly reduced. Although partially deprived of rapid eye movements for as long as 7 days, the cats showed no compensatory rise in rapid eye movement time during the recovery period, but controls equally deprived gave significant rebounds. Rapid eye movement time of anesthetized cats was not affected by current that usually produces convulsions; it was lowered in animals convulsed with metrazol, but the same dosage of this drug, administered so as to avoid convulsions, had little effect. It appears that some aspect of the convulsion is responsible for lowering the rapid eye movement time.
doi_str_mv	10.1126/science.154.3747.396
format	article
fullrecord	<record><control><sourceid>jstor_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_84182830</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><jstor_id>1719270</jstor_id><sourcerecordid>1719270</sourcerecordid><originalsourceid>FETCH-LOGICAL-c353t-eb7764beba7698fbb8008d2cc6fc1879bddc42bac2ed1409b8a31b908d956e193</originalsourceid><addsrcrecordid>eNpFkE9LwzAchoMoc06_wYScvHUmTdsk3mTMPzBRnOIxJOmvrLNratIO9u3tWNHTe3je9z08CE0pmVEaZ7fBllBbmNE0mTGe8BmT2QkaUyLTSMaEnaIxISyLBOHpOboIYUNIzyQboVEqKSdCjNHXqgJo7vCqaxoPIZSuxq7A77opc7zYA35xO9hC3eK3tQ6Ayxq3a8Bz3WJdtODxogLbemddveuqUO4Ar9bOfl-is0JXAa6GnKDPh8XH_Clavj4-z--XkWUpayMwnGeJAaN5JkVhjCBE5LG1WWGp4NLkuU1io20MOU2INEIzamTfkWkGVLIJujn-Nt79dBBatS2DharSNbguKJFQEQtG-mJyLFrvQvBQqMaXW-33ihJ18KkGn6r3qQ4-Ve-zn10P_53ZQv43GgT2fHrkm9A6___JqYw5Yb__ZH00</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>84182830</pqid></control><display><type>article</type><title>Sleep: Suppression of Rapid Eye Movement Phase in the Cat after Electroconvulsive Shock</title><source>American Association for the Advancement of Science</source><source>JSTOR Archival Journals and Primary Sources Collection</source><creator>Cohen, Harry B. ; Dement, William C.</creator><creatorcontrib>Cohen, Harry B. ; Dement, William C.</creatorcontrib><description>Electroconvulsive shock, administered for 5 to 7 days, reduced the daily rapid eye movement sleep time of seven cats to as little as 28 percent of base line levels. After day 4, eye movements during periods of cortical activation without tonic electromyographic activity were greatly reduced. Although partially deprived of rapid eye movements for as long as 7 days, the cats showed no compensatory rise in rapid eye movement time during the recovery period, but controls equally deprived gave significant rebounds. Rapid eye movement time of anesthetized cats was not affected by current that usually produces convulsions; it was lowered in animals convulsed with metrazol, but the same dosage of this drug, administered so as to avoid convulsions, had little effect. It appears that some aspect of the convulsion is responsible for lowering the rapid eye movement time.</description><identifier>ISSN: 0036-8075</identifier><identifier>EISSN: 1095-9203</identifier><identifier>DOI: 10.1126/science.154.3747.396</identifier><identifier>PMID: 5917088</identifier><language>eng</language><publisher>United States: American Association for the Advancement of Science</publisher><subject>Animals ; Cats ; Convulsions ; Electroconvulsive Therapy ; Ethyl Ethers - pharmacology ; Eye Movements ; Female ; Hemoglobins ; In rem ; Intravenous injections ; Male ; Pentylenetetrazole - pharmacology ; Phenotypes ; Rapid eye movement sleep ; Sleep ; Sleep deprivation</subject><ispartof>Science (American Association for the Advancement of Science), 1966-10, Vol.154 (3747), p.396-398</ispartof><rights>Copyright 1966 American Association for the Advancement of Science</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c353t-eb7764beba7698fbb8008d2cc6fc1879bddc42bac2ed1409b8a31b908d956e193</citedby><cites>FETCH-LOGICAL-c353t-eb7764beba7698fbb8008d2cc6fc1879bddc42bac2ed1409b8a31b908d956e193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/1719270$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/1719270$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,2871,2872,27901,27902,58213,58446</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5917088$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cohen, Harry B.</creatorcontrib><creatorcontrib>Dement, William C.</creatorcontrib><title>Sleep: Suppression of Rapid Eye Movement Phase in the Cat after Electroconvulsive Shock</title><title>Science (American Association for the Advancement of Science)</title><addtitle>Science</addtitle><description>Electroconvulsive shock, administered for 5 to 7 days, reduced the daily rapid eye movement sleep time of seven cats to as little as 28 percent of base line levels. After day 4, eye movements during periods of cortical activation without tonic electromyographic activity were greatly reduced. Although partially deprived of rapid eye movements for as long as 7 days, the cats showed no compensatory rise in rapid eye movement time during the recovery period, but controls equally deprived gave significant rebounds. Rapid eye movement time of anesthetized cats was not affected by current that usually produces convulsions; it was lowered in animals convulsed with metrazol, but the same dosage of this drug, administered so as to avoid convulsions, had little effect. It appears that some aspect of the convulsion is responsible for lowering the rapid eye movement time.</description><subject>Animals</subject><subject>Cats</subject><subject>Convulsions</subject><subject>Electroconvulsive Therapy</subject><subject>Ethyl Ethers - pharmacology</subject><subject>Eye Movements</subject><subject>Female</subject><subject>Hemoglobins</subject><subject>In rem</subject><subject>Intravenous injections</subject><subject>Male</subject><subject>Pentylenetetrazole - pharmacology</subject><subject>Phenotypes</subject><subject>Rapid eye movement sleep</subject><subject>Sleep</subject><subject>Sleep deprivation</subject><issn>0036-8075</issn><issn>1095-9203</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1966</creationdate><recordtype>article</recordtype><recordid>eNpFkE9LwzAchoMoc06_wYScvHUmTdsk3mTMPzBRnOIxJOmvrLNratIO9u3tWNHTe3je9z08CE0pmVEaZ7fBllBbmNE0mTGe8BmT2QkaUyLTSMaEnaIxISyLBOHpOboIYUNIzyQboVEqKSdCjNHXqgJo7vCqaxoPIZSuxq7A77opc7zYA35xO9hC3eK3tQ6Ayxq3a8Bz3WJdtODxogLbemddveuqUO4Ar9bOfl-is0JXAa6GnKDPh8XH_Clavj4-z--XkWUpayMwnGeJAaN5JkVhjCBE5LG1WWGp4NLkuU1io20MOU2INEIzamTfkWkGVLIJujn-Nt79dBBatS2DharSNbguKJFQEQtG-mJyLFrvQvBQqMaXW-33ihJ18KkGn6r3qQ4-Ve-zn10P_53ZQv43GgT2fHrkm9A6___JqYw5Yb__ZH00</recordid><startdate>19661021</startdate><enddate>19661021</enddate><creator>Cohen, Harry B.</creator><creator>Dement, William C.</creator><general>American Association for the Advancement of Science</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19661021</creationdate><title>Sleep: Suppression of Rapid Eye Movement Phase in the Cat after Electroconvulsive Shock</title><author>Cohen, Harry B. ; Dement, William C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c353t-eb7764beba7698fbb8008d2cc6fc1879bddc42bac2ed1409b8a31b908d956e193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1966</creationdate><topic>Animals</topic><topic>Cats</topic><topic>Convulsions</topic><topic>Electroconvulsive Therapy</topic><topic>Ethyl Ethers - pharmacology</topic><topic>Eye Movements</topic><topic>Female</topic><topic>Hemoglobins</topic><topic>In rem</topic><topic>Intravenous injections</topic><topic>Male</topic><topic>Pentylenetetrazole - pharmacology</topic><topic>Phenotypes</topic><topic>Rapid eye movement sleep</topic><topic>Sleep</topic><topic>Sleep deprivation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cohen, Harry B.</creatorcontrib><creatorcontrib>Dement, William C.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Science (American Association for the Advancement of Science)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cohen, Harry B.</au><au>Dement, William C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sleep: Suppression of Rapid Eye Movement Phase in the Cat after Electroconvulsive Shock</atitle><jtitle>Science (American Association for the Advancement of Science)</jtitle><addtitle>Science</addtitle><date>1966-10-21</date><risdate>1966</risdate><volume>154</volume><issue>3747</issue><spage>396</spage><epage>398</epage><pages>396-398</pages><issn>0036-8075</issn><eissn>1095-9203</eissn><abstract>Electroconvulsive shock, administered for 5 to 7 days, reduced the daily rapid eye movement sleep time of seven cats to as little as 28 percent of base line levels. After day 4, eye movements during periods of cortical activation without tonic electromyographic activity were greatly reduced. Although partially deprived of rapid eye movements for as long as 7 days, the cats showed no compensatory rise in rapid eye movement time during the recovery period, but controls equally deprived gave significant rebounds. Rapid eye movement time of anesthetized cats was not affected by current that usually produces convulsions; it was lowered in animals convulsed with metrazol, but the same dosage of this drug, administered so as to avoid convulsions, had little effect. It appears that some aspect of the convulsion is responsible for lowering the rapid eye movement time.</abstract><cop>United States</cop><pub>American Association for the Advancement of Science</pub><pmid>5917088</pmid><doi>10.1126/science.154.3747.396</doi><tpages>3</tpages></addata></record>
fulltext	fulltext
identifier	ISSN: 0036-8075
ispartof	Science (American Association for the Advancement of Science), 1966-10, Vol.154 (3747), p.396-398
issn	0036-8075 1095-9203
language	eng
recordid	cdi_proquest_miscellaneous_84182830
source	American Association for the Advancement of Science; JSTOR Archival Journals and Primary Sources Collection
subjects	Animals Cats Convulsions Electroconvulsive Therapy Ethyl Ethers - pharmacology Eye Movements Female Hemoglobins In rem Intravenous injections Male Pentylenetetrazole - pharmacology Phenotypes Rapid eye movement sleep Sleep Sleep deprivation
title	Sleep: Suppression of Rapid Eye Movement Phase in the Cat after Electroconvulsive Shock
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T18%3A15%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-jstor_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sleep:%20Suppression%20of%20Rapid%20Eye%20Movement%20Phase%20in%20the%20Cat%20after%20Electroconvulsive%20Shock&rft.jtitle=Science%20(American%20Association%20for%20the%20Advancement%20of%20Science)&rft.au=Cohen,%20Harry%20B.&rft.date=1966-10-21&rft.volume=154&rft.issue=3747&rft.spage=396&rft.epage=398&rft.pages=396-398&rft.issn=0036-8075&rft.eissn=1095-9203&rft_id=info:doi/10.1126/science.154.3747.396&rft_dat=%3Cjstor_proqu%3E1719270%3C/jstor_proqu%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c353t-eb7764beba7698fbb8008d2cc6fc1879bddc42bac2ed1409b8a31b908d956e193%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=84182830&rft_id=info:pmid/5917088&rft_jstor_id=1719270&rfr_iscdi=true