The Biological Characterization of the Hemolysin from the El Tor Variety of Vibrio cholerae

The biological and immunoserological properties of crude and purified hemolysin obtained from culture superna-tants of an El Tor vibrio were studied. The hemolysin appears to be an antigenic substance separate from mouse lethal toxin, proteinase, lecithinase, neuraminidase and mucinase. A variable p...

Full description

Saved in:
Bibliographic Details
Published in:The Journal of infectious diseases 1966-06, Vol.116 (3), p.363-371
Main Authors: Watanabe, Y., Verwey, W. F.
Format: Article
Language:English
Subjects:
Agglutination Tests
Animals
Antibodies
Antibody Formation
Antigens
Antiserum
Dosage
Erythrocytes
Hemolysin Proteins
Hyaluronoglucosaminidase
Immunodiffusion
In Vitro Techniques
Lethal dose
Molecules
Neuraminidase
Neutralization Tests
Phospholipases
Rabbits
Toxins
Vibrio
Vibrio - immunology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The biological and immunoserological properties of crude and purified hemolysin obtained from culture superna-tants of an El Tor vibrio were studied. The hemolysin appears to be an antigenic substance separate from mouse lethal toxin, proteinase, lecithinase, neuraminidase and mucinase. A variable proportion complexing between hemolysin and dermonecrotic toxin has been suggested. The purified hemolysin induces the formation of precipitating antibody which neutralizes its hemolytic activity but is not protective in mice or vibriocidal against homologous organisms.
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/116.3.363