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Micelle Formation between 5-Hydroxytryptamine and Adenosine Triphosphate in Platelet Storage Organelles

As judged by analytical ultracentrifugation, 5-hydroxytryptamine and adenosine-5′-triphosphate form micelles in artificial mixtures and also in storage organelles containing 5-hydroxytryptamine of blood platelets of rabbits. Their average apparent molecular weights depend on the concentration and on...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1969-08, Vol.165 (3896), p.913-914
Main Authors: Berneis, K. H., Da Prada, M., Pletscher, A.
Format: Article
Language:English
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Summary:As judged by analytical ultracentrifugation, 5-hydroxytryptamine and adenosine-5′-triphosphate form micelles in artificial mixtures and also in storage organelles containing 5-hydroxytryptamine of blood platelets of rabbits. Their average apparent molecular weights depend on the concentration and on the molar ratio of the two constituents. The 5-hydroxytryptamine and adenosine triphosphate of these 5-hydroxytryptamine organelles may be stored in vivo together as micelles with apparent molecular weights of several hundred thousands or more.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.165.3896.913