Exchange transfusions: blood volume, increment volume, efficiency

We wish to call attention to an apparently common misconception about the efficiency of exchange transfusions. The mechanics of the procedure are: a substance (bilirubin and/or antibody-coated red cells) is washed out of a compartment (the baby's blood volume) by the removal of a fraction of th...

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Bibliographic Details
Published in:Pediatrics (Evanston) 1966-11, Vol.38 (5), p.927-929
Main Authors: Phibbs, R H, Sproul, A
Format: Article
Language:English
Subjects:
Bilirubin - blood
Blood Volume
Exchange Transfusion, Whole Blood
Humans
Infant, Newborn
Online Access:Get full text
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Description
Summary:We wish to call attention to an apparently common misconception about the efficiency of exchange transfusions. The mechanics of the procedure are: a substance (bilirubin and/or antibody-coated red cells) is washed out of a compartment (the baby's blood volume) by the removal of a fraction of that compartment and its replacement by an equal volume of diluent (donor blood). This flushing process is repeated many times, usually until the total volume replaced is 2 to 3 times the volume of the compartment itself.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.38.5.927