Leukocyte Mitosis: Suppression in vitro Associated with Acute Infectious Hepatitis

Inhibition of mitosis in vitro was observed in leukocytes from patients with acute infectious hepatitis. Similarly, in cultures of normal leukocytes, after the addition of small amounts of serum from patients with hepatitis, mitosis was suppressed. Although the incidence of mitosis became normal in...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1967-01, Vol.155 (3758), p.80-81
Main Authors: Mella, Barbara, Lang, David J.
Format: Article
Language:English
Subjects:
Blood
Cell Division
Chromosomes
Epidemiology
Hepatitis
Hepatitis A
Hepatitis A - blood
Humans
In Vitro Techniques
Leukocytes
Metaphase
Mitosis
Viruses
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Summary:Inhibition of mitosis in vitro was observed in leukocytes from patients with acute infectious hepatitis. Similarly, in cultures of normal leukocytes, after the addition of small amounts of serum from patients with hepatitis, mitosis was suppressed. Although the incidence of mitosis became normal in leukocytes from convalescent patients, there were chromosomal abnormalities.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.155.3758.80