Bacteriophage S13: a 7th gene

Genetic complementation tests of ochre-type suppressible mutants of bacteriophage S13 have revealed a seventh gene. A mutation of this gene has no significant effect on synthesis of the phage replicative form DNA, but like five other phage genes it prevents the appearance of single-stranded DNA. Wit...

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Bibliographic Details
Published in:Science (American Association for the Advancement of Science) 1967-05, Vol.156 (3776), p.824-825
Main Authors: Tessman, I, Ishiwa, H, Kumar, S, Baker, R
Format: Article
Language:English
Subjects:
Coliphages
DNA, Viral - biosynthesis
Genes
Molecular Biology
Mutation
Viral Proteins - biosynthesis
Online Access:Get full text
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Summary:Genetic complementation tests of ochre-type suppressible mutants of bacteriophage S13 have revealed a seventh gene. A mutation of this gene has no significant effect on synthesis of the phage replicative form DNA, but like five other phage genes it prevents the appearance of single-stranded DNA. With the new gene, it seems likely that approximately 70 to 100 percent of the phage genes are accounted for.
ISSN:0036-8075
DOI:10.1126/science.156.3776.824