Differentiation of Synaptic Bulbs in Clarke's Column

INVESTIGATIONS of the fine structure of synaptic junctions have revealed a morphological differentiation of apposed synaptic membranes and associated presynaptic and postsynaptic elements 1–4 . Presynaptic terminals have been shown to contain agranular synaptic vesicles, although larger granular ves...

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Bibliographic Details
Published in:Nature (London) 1967-04, Vol.214 (5086), p.391-392
Main Authors: SEDAR, ALBERT W., MOSKOWITZ, NORMAN
Format: Article
Language:English
Subjects:
Animals
Axons - cytology
Haplorhini
Histological Techniques
Humanities and Social Sciences
letter
Male
Microscopy, Electron
Motor Neurons
multidisciplinary
Science
Science (multidisciplinary)
Spinal Cord - cytology
Staining and Labeling
Synapses - cytology
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Summary:INVESTIGATIONS of the fine structure of synaptic junctions have revealed a morphological differentiation of apposed synaptic membranes and associated presynaptic and postsynaptic elements 1–4 . Presynaptic terminals have been shown to contain agranular synaptic vesicles, although larger granular vesicles have also been reported 5,6 . Two kinds of axonal terminals were recently identified, one of which contains spherical, and the other flattened, agranular vesicles. The observation was made in boutons synapsing with dendrites in the molecular layer of the cerebellum 7 and in boutons synapsing with anterior horn cells of the spinal cord 8 . This communication reports observations on two forms of synaptic vesicles which can be used to differentiate two types of boutons found within Clarke's column of the monkey ( Saimiri sciureus ). This nucleus of the dorsal column is found in the spinal cord at thoracic and upper lumbar levels. It receives proprioceptive impulses chiefly from neuromuscular spindles and Golgi tendon organs. These impulses are relayed to the cerebellum by spinocerebellar tracts.
ISSN:0028-0836
1476-4687
DOI:10.1038/214391a0