CARDIAC EFFECTS OF ADRENALINE AND FELYPRESSIN AS VASOCONSTRICTORS IN LOCAL ANAESTHESIA FOR ORAL SURGERY UNDER DIAZEPAM SEDATION

Brief precipitate heart rate rises of up to 40 beats/min were observed in nineteen of twenty-seven dental patients receiving local anaesthesia with 2 per cent lignocaine with adrenaline (1:80,000). No such rises were seen after 3 per cent prilocaine with felypressin (0.03 i.u./ml) which therefore ma...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1970-02, Vol.42 (2), p.174-176
Main Authors: AELLIG, W.H., LAURENCE, D.R., O'NEIL, R., VERRILL, P.J.
Format: Article
Language:English
Subjects:
Adult
Anesthesia, Dental
Anesthesia, Local
Blood Pressure - drug effects
Cardiovascular Diseases
Diazepam
Electrocardiography
Epinephrine - pharmacology
Felypressin
Female
Heart Rate - drug effects
Humans
Male
Middle Aged
Vasoconstrictor Agents
Vasopressins - pharmacology
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Description
Summary:Brief precipitate heart rate rises of up to 40 beats/min were observed in nineteen of twenty-seven dental patients receiving local anaesthesia with 2 per cent lignocaine with adrenaline (1:80,000). No such rises were seen after 3 per cent prilocaine with felypressin (0.03 i.u./ml) which therefore may be preferable for patients with cardiovascular disease.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/42.2.174