Increased Lactate Dehydrogenase 3 in Serum after Myocardial Infarction

SINCE the first report of lactate dehydrogenase (LDH) isoenzymes in human serum 1 a variety of different techniques has been employed to demonstrate them in serum and tissues. There is general agreement, however, that heart muscle contains predominantly the fast-moving isoenzymes lactate dehydrogena...

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Bibliographic Details
Published in:Nature (London) 1967-07, Vol.215 (5098), p.287-289
Main Authors: WARBURTON, F. G, ALLAN, E, LAING, G. S, WADDECAR, J
Format: Article
Language:English
Subjects:
Chemistry, Clinical
Electrophoresis
Erythrocytes - enzymology
Heart Atria - enzymology
Heart Septum - enzymology
Heart Ventricles - enzymology
Humanities and Social Sciences
Humans
Isoenzymes
L-Lactate Dehydrogenase - blood
letter
multidisciplinary
Myocardial Infarction - enzymology
Myocardium - enzymology
Science
Science (multidisciplinary)
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Summary:SINCE the first report of lactate dehydrogenase (LDH) isoenzymes in human serum 1 a variety of different techniques has been employed to demonstrate them in serum and tissues. There is general agreement, however, that heart muscle contains predominantly the fast-moving isoenzymes lactate dehydrogenase 1 and 2 and that these are present in increased quantities in the sera of patients who have suffered a myocardial infarction, remaining demonstrably elevated for 1–3 weeks after the onset of the attack 2 .
ISSN:0028-0836
1476-4687
DOI:10.1038/215287a0