Predicting the yield of (177)Lu radionuclide produced by the cyclic irradiation technique

The feasibility study on the production of (177)Lu radioisotope using a low power research reactor has been conducted. A reliable method for predicting the yield of (177)Lu produced using the cyclic activation technique based on the Westcott formalism has been established. A specific activity of 243...

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Bibliographic Details
Published in:Applied radiation and isotopes 2011-03, Vol.69 (3), p.588-593
Main Authors: Odame Duodu, Godfred, Akaho, Edward H K, Serfor-Armah, Yaw, Nyarko, Benjamin J B, Afi Achoribo, Elom
Format: Article
Language:English
Subjects:
Beta Particles
Lutetium
Nuclear Reactors
Radioisotopes
Radiopharmaceuticals - chemical synthesis
Online Access:Get full text
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Summary:The feasibility study on the production of (177)Lu radioisotope using a low power research reactor has been conducted. A reliable method for predicting the yield of (177)Lu produced using the cyclic activation technique based on the Westcott formalism has been established. A specific activity of 243.24 mCi/g was obtained when a (176)Lu(2)O(3) of natural abundance was irradiated for 4 h and decayed for 20 h for four cycles at GHARR-1 with a neutron flux of 5.0×10(11) ncm(-2)s(-1).
ISSN:1872-9800
DOI:10.1016/j.apradiso.2010.12.002