Loading…
Controversies in the physiological basis of the ‘anaerobic threshold’ and their implications for clinical cardiopulmonary exercise testing
Summary This article reviews the notion of the ‘anaerobic threshold’ in the context of cardiopulmonary exercise testing. Primarily, this is a review of the proposed mechanisms underlying the ventilatory and lactate response to incremental exercise, which is important to the clinical interpretation o...
Saved in:
| Published in: | Anaesthesia 2011-02, Vol.66 (2), p.111-123 |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c5094-ecb614941bd1eb08b1ed55c9ab6a3cd814ad68658b8885b01f5feaa7040019c13 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c5094-ecb614941bd1eb08b1ed55c9ab6a3cd814ad68658b8885b01f5feaa7040019c13 |
| container_end_page | 123 |
| container_issue | 2 |
| container_start_page | 111 |
| container_title | Anaesthesia |
| container_volume | 66 |
| creator | Hopker, J. G. Jobson, S. A. Pandit, J. J. |
| description | Summary
This article reviews the notion of the ‘anaerobic threshold’ in the context of cardiopulmonary exercise testing. Primarily, this is a review of the proposed mechanisms underlying the ventilatory and lactate response to incremental exercise, which is important to the clinical interpretation of an exercise test. Since such tests are often conducted for risk stratification before major surgery, a failure to locate or justify the existence of an anaerobic threshold will have some implications for clinical practice. We also consider alternative endpoints within the exercise response that might be better used to indicate a patient’s capacity to cope with the metabolic demands encountered both during and following major surgery. |
| doi_str_mv | 10.1111/j.1365-2044.2010.06604.x |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_847279387</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2246785901</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5094-ecb614941bd1eb08b1ed55c9ab6a3cd814ad68658b8885b01f5feaa7040019c13</originalsourceid><addsrcrecordid>eNqNkUGP1CAYhonRuOPqXzDExOilI1BK6cVkMlldk41e9EyA0h0mFCq0OnPbX-BZ_97-kqUz45p4MHKBfN_zvcD7AgAxWuK83myXuGRVQRClS4JyFTGG6HL3ACzuGw_BAiFUFoSi5gw8SWmLECYc88fgjGBS0YazBfixDn6M4ZuJyZoErYfjxsBhs082uHBttXRQyWQTDN2hdXvzU3ppYlBW50I0aRNce3vzC0rfzoSN0PaDy5OjDT7BLkSonfUHKS1ja8MwuT54GffQ7EzUNhk4mjRaf_0UPOqkS-bZaT8HX95dfF5fFlef3n9Yr64KXaGGFkYrhmlDsWqxUYgrbNqq0o1UTJa65ZjKlnFWccU5rxTCXdUZKWtEsweNxuU5eHXUHWL4OuW7RW-TNs5Jb8KUBKc1qZuS15l8_U8SI4wJqjmlGX3xF7oNU_T5H1mPNSWijGSIHyEdQ0rRdGKIts9eZCUxhyu2Ys5QzBmKOVxxCFfs8ujzk_6ketPeD_5OMwMvT4BM2e0uSp_N_cOVDeL1gXt75L5bZ_b__QCx-ri6mI_lHWICxCg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>846930462</pqid></control><display><type>article</type><title>Controversies in the physiological basis of the ‘anaerobic threshold’ and their implications for clinical cardiopulmonary exercise testing</title><source>Wiley</source><creator>Hopker, J. G. ; Jobson, S. A. ; Pandit, J. J.</creator><creatorcontrib>Hopker, J. G. ; Jobson, S. A. ; Pandit, J. J.</creatorcontrib><description>Summary
This article reviews the notion of the ‘anaerobic threshold’ in the context of cardiopulmonary exercise testing. Primarily, this is a review of the proposed mechanisms underlying the ventilatory and lactate response to incremental exercise, which is important to the clinical interpretation of an exercise test. Since such tests are often conducted for risk stratification before major surgery, a failure to locate or justify the existence of an anaerobic threshold will have some implications for clinical practice. We also consider alternative endpoints within the exercise response that might be better used to indicate a patient’s capacity to cope with the metabolic demands encountered both during and following major surgery.</description><identifier>ISSN: 0003-2409</identifier><identifier>EISSN: 1365-2044</identifier><identifier>DOI: 10.1111/j.1365-2044.2010.06604.x</identifier><identifier>PMID: 21254986</identifier><identifier>CODEN: ANASAB</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Anaerobic threshold ; Anaerobic Threshold - physiology ; Anesthesia ; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy ; Biological and medical sciences ; Cardiovascular system ; Carotid Body - physiology ; Exercise ; Exercise - physiology ; Exercise Test - methods ; Failure ; Humans ; Hyperventilation - physiopathology ; Lactic acid ; Lactic Acid - metabolism ; Medical sciences ; Medical tests ; Motor performance tests ; Patients ; Physiology ; Risk factors ; Surgery ; Terminology as Topic</subject><ispartof>Anaesthesia, 2011-02, Vol.66 (2), p.111-123</ispartof><rights>2011 The Authors. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland</rights><rights>2015 INIST-CNRS</rights><rights>2011 The Authors. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5094-ecb614941bd1eb08b1ed55c9ab6a3cd814ad68658b8885b01f5feaa7040019c13</citedby><cites>FETCH-LOGICAL-c5094-ecb614941bd1eb08b1ed55c9ab6a3cd814ad68658b8885b01f5feaa7040019c13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23908786$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21254986$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hopker, J. G.</creatorcontrib><creatorcontrib>Jobson, S. A.</creatorcontrib><creatorcontrib>Pandit, J. J.</creatorcontrib><title>Controversies in the physiological basis of the ‘anaerobic threshold’ and their implications for clinical cardiopulmonary exercise testing</title><title>Anaesthesia</title><addtitle>Anaesthesia</addtitle><description>Summary
This article reviews the notion of the ‘anaerobic threshold’ in the context of cardiopulmonary exercise testing. Primarily, this is a review of the proposed mechanisms underlying the ventilatory and lactate response to incremental exercise, which is important to the clinical interpretation of an exercise test. Since such tests are often conducted for risk stratification before major surgery, a failure to locate or justify the existence of an anaerobic threshold will have some implications for clinical practice. We also consider alternative endpoints within the exercise response that might be better used to indicate a patient’s capacity to cope with the metabolic demands encountered both during and following major surgery.</description><subject>Anaerobic threshold</subject><subject>Anaerobic Threshold - physiology</subject><subject>Anesthesia</subject><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Cardiovascular system</subject><subject>Carotid Body - physiology</subject><subject>Exercise</subject><subject>Exercise - physiology</subject><subject>Exercise Test - methods</subject><subject>Failure</subject><subject>Humans</subject><subject>Hyperventilation - physiopathology</subject><subject>Lactic acid</subject><subject>Lactic Acid - metabolism</subject><subject>Medical sciences</subject><subject>Medical tests</subject><subject>Motor performance tests</subject><subject>Patients</subject><subject>Physiology</subject><subject>Risk factors</subject><subject>Surgery</subject><subject>Terminology as Topic</subject><issn>0003-2409</issn><issn>1365-2044</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><recordid>eNqNkUGP1CAYhonRuOPqXzDExOilI1BK6cVkMlldk41e9EyA0h0mFCq0OnPbX-BZ_97-kqUz45p4MHKBfN_zvcD7AgAxWuK83myXuGRVQRClS4JyFTGG6HL3ACzuGw_BAiFUFoSi5gw8SWmLECYc88fgjGBS0YazBfixDn6M4ZuJyZoErYfjxsBhs082uHBttXRQyWQTDN2hdXvzU3ppYlBW50I0aRNce3vzC0rfzoSN0PaDy5OjDT7BLkSonfUHKS1ja8MwuT54GffQ7EzUNhk4mjRaf_0UPOqkS-bZaT8HX95dfF5fFlef3n9Yr64KXaGGFkYrhmlDsWqxUYgrbNqq0o1UTJa65ZjKlnFWccU5rxTCXdUZKWtEsweNxuU5eHXUHWL4OuW7RW-TNs5Jb8KUBKc1qZuS15l8_U8SI4wJqjmlGX3xF7oNU_T5H1mPNSWijGSIHyEdQ0rRdGKIts9eZCUxhyu2Ys5QzBmKOVxxCFfs8ujzk_6ketPeD_5OMwMvT4BM2e0uSp_N_cOVDeL1gXt75L5bZ_b__QCx-ri6mI_lHWICxCg</recordid><startdate>201102</startdate><enddate>201102</enddate><creator>Hopker, J. G.</creator><creator>Jobson, S. A.</creator><creator>Pandit, J. J.</creator><general>Blackwell Publishing Ltd</general><general>Wiley-Blackwell</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7U7</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>7TS</scope><scope>7X8</scope></search><sort><creationdate>201102</creationdate><title>Controversies in the physiological basis of the ‘anaerobic threshold’ and their implications for clinical cardiopulmonary exercise testing</title><author>Hopker, J. G. ; Jobson, S. A. ; Pandit, J. J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5094-ecb614941bd1eb08b1ed55c9ab6a3cd814ad68658b8885b01f5feaa7040019c13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Anaerobic threshold</topic><topic>Anaerobic Threshold - physiology</topic><topic>Anesthesia</topic><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Cardiovascular system</topic><topic>Carotid Body - physiology</topic><topic>Exercise</topic><topic>Exercise - physiology</topic><topic>Exercise Test - methods</topic><topic>Failure</topic><topic>Humans</topic><topic>Hyperventilation - physiopathology</topic><topic>Lactic acid</topic><topic>Lactic Acid - metabolism</topic><topic>Medical sciences</topic><topic>Medical tests</topic><topic>Motor performance tests</topic><topic>Patients</topic><topic>Physiology</topic><topic>Risk factors</topic><topic>Surgery</topic><topic>Terminology as Topic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hopker, J. G.</creatorcontrib><creatorcontrib>Jobson, S. A.</creatorcontrib><creatorcontrib>Pandit, J. J.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Physical Education Index</collection><collection>MEDLINE - Academic</collection><jtitle>Anaesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hopker, J. G.</au><au>Jobson, S. A.</au><au>Pandit, J. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Controversies in the physiological basis of the ‘anaerobic threshold’ and their implications for clinical cardiopulmonary exercise testing</atitle><jtitle>Anaesthesia</jtitle><addtitle>Anaesthesia</addtitle><date>2011-02</date><risdate>2011</risdate><volume>66</volume><issue>2</issue><spage>111</spage><epage>123</epage><pages>111-123</pages><issn>0003-2409</issn><eissn>1365-2044</eissn><coden>ANASAB</coden><abstract>Summary
This article reviews the notion of the ‘anaerobic threshold’ in the context of cardiopulmonary exercise testing. Primarily, this is a review of the proposed mechanisms underlying the ventilatory and lactate response to incremental exercise, which is important to the clinical interpretation of an exercise test. Since such tests are often conducted for risk stratification before major surgery, a failure to locate or justify the existence of an anaerobic threshold will have some implications for clinical practice. We also consider alternative endpoints within the exercise response that might be better used to indicate a patient’s capacity to cope with the metabolic demands encountered both during and following major surgery.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>21254986</pmid><doi>10.1111/j.1365-2044.2010.06604.x</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0003-2409 |
| ispartof | Anaesthesia, 2011-02, Vol.66 (2), p.111-123 |
| issn | 0003-2409 1365-2044 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_847279387 |
| source | Wiley |
| subjects | Anaerobic threshold Anaerobic Threshold - physiology Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Cardiovascular system Carotid Body - physiology Exercise Exercise - physiology Exercise Test - methods Failure Humans Hyperventilation - physiopathology Lactic acid Lactic Acid - metabolism Medical sciences Medical tests Motor performance tests Patients Physiology Risk factors Surgery Terminology as Topic |
| title | Controversies in the physiological basis of the ‘anaerobic threshold’ and their implications for clinical cardiopulmonary exercise testing |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T22%3A58%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Controversies%20in%20the%20physiological%20basis%20of%20the%20%E2%80%98anaerobic%20threshold%E2%80%99%20and%20their%20implications%20for%20clinical%20cardiopulmonary%20exercise%20testing&rft.jtitle=Anaesthesia&rft.au=Hopker,%20J.%20G.&rft.date=2011-02&rft.volume=66&rft.issue=2&rft.spage=111&rft.epage=123&rft.pages=111-123&rft.issn=0003-2409&rft.eissn=1365-2044&rft.coden=ANASAB&rft_id=info:doi/10.1111/j.1365-2044.2010.06604.x&rft_dat=%3Cproquest_cross%3E2246785901%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c5094-ecb614941bd1eb08b1ed55c9ab6a3cd814ad68658b8885b01f5feaa7040019c13%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=846930462&rft_id=info:pmid/21254986&rfr_iscdi=true |