Clinical and hemodynamic predictors of natriuretic peptide elevation among aortic valve disease patients

Abstract We investigated the relative contribution of hemodynamic and clinical factors to serum natriuretic peptide elevation in seventy-one patients with either aortic stenosis or aortic regurgitation. We found that pulmonary hypertension, heart failure and renal failure are the most powerful indep...

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Bibliographic Details
Published in:International journal of cardiology 2011-02, Vol.146 (3), p.e66-e68
Main Authors: Liska, Branislav, Khattab, Ahmed A, Sherif, Mohammad A, Abdel-Wahab, Mohamed, Kassner, Guido, Balum, Abdallah, Richardt, Gert
Format: Article
Language:English
Subjects:
Aortic valve disease
Aortic Valve Insufficiency - blood
Aortic Valve Insufficiency - physiopathology
Aortic Valve Stenosis - blood
Aortic Valve Stenosis - physiopathology
BNP
Cardiovascular
Hemodynamics
Humans
Natriuretic Peptides - blood
Predictive Value of Tests
Prospective Studies
Pulmonary hypertension
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Summary:Abstract We investigated the relative contribution of hemodynamic and clinical factors to serum natriuretic peptide elevation in seventy-one patients with either aortic stenosis or aortic regurgitation. We found that pulmonary hypertension, heart failure and renal failure are the most powerful independent predictors of natriuretic peptide elevation in patients with aortic valve disease, irrespective of the type or severity of valvular lesion itself.
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2008.12.211