The oxidative stress status in diabetes mellitus and diabetic nephropathy

The aim of this study is to assess the oxidative stress status in diabetes mellitus (DM) and diabetic nephropathy. The study group comprised 40 control subjects, 40 type 2 DM patients without complications and 37 diabetic nephropathies. Compared with control subjects, superoxide dismutase, glutathio...

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Bibliographic Details
Published in:Acta diabetologica 2010-12, Vol.47 (Suppl 1), p.71-76
Main Authors: Pan, Hong-zhi, Zhang, Lin, Guo, Mei-yi, Sui, Hong, Li, Hui, Wu, Wei-hua, Qu, Nai-qiang, Liang, Mei-hua, Chang, Dong
Format: Article
Language:English
Subjects:
Adult
Aged
Case-Control Studies
Catalase - metabolism
Deoxyguanosine - analogs & derivatives
Diabetes
Diabetes Mellitus, Type 2 - complications
Diabetes Mellitus, Type 2 - enzymology
Diabetes Mellitus, Type 2 - metabolism
Diabetic Nephropathies - enzymology
Diabetic Nephropathies - etiology
Diabetic Nephropathies - metabolism
Female
Glutathione - blood
Glutathione Peroxidase - metabolism
Humans
Internal Medicine
Kidney diseases
Male
Malondialdehyde - blood
Medicine
Medicine & Public Health
Metabolic Diseases
Middle Aged
Original Article
Oxidative Stress
Pathogenesis
Superoxide Dismutase - metabolism
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Summary:The aim of this study is to assess the oxidative stress status in diabetes mellitus (DM) and diabetic nephropathy. The study group comprised 40 control subjects, 40 type 2 DM patients without complications and 37 diabetic nephropathies. Compared with control subjects, superoxide dismutase, glutathione peroxidase, catalase, vitamin C were decreased ( P  
ISSN:0940-5429
1432-5233
DOI:10.1007/s00592-009-0128-1