Apparent renal disease due to elevated creatinine levels associated with the use of boldenone

The widespread use of reporting estimated glomerular filtration rate (eGFR) alongside serum creatinine has led to a heightened appreciation of renal disease. However, creatinine is recognized as an insensitive marker of true GFR and therefore can lead to misdiagnosis of renal dysfunction in the abse...

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Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 2011-02, Vol.26 (2), p.744-747
Main Authors: WINNETT, Georgia, CRANFIELD, Lesley, ALMOND, Michael
Format: Article
Language:English
Subjects:
Adult
Anabolic Agents - adverse effects
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Creatinine - blood
Emergency and intensive care: renal failure. Dialysis management
Humans
Intensive care medicine
Kidney Diseases - blood
Kidney Diseases - chemically induced
Male
Medical sciences
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Renal failure
Testosterone - adverse effects
Testosterone - analogs & derivatives
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Summary:The widespread use of reporting estimated glomerular filtration rate (eGFR) alongside serum creatinine has led to a heightened appreciation of renal disease. However, creatinine is recognized as an insensitive marker of true GFR and therefore can lead to misdiagnosis of renal dysfunction in the absence of true pathology. We report the case of a 37-year-old male referred due to abnormal eGFR and creatinine in the absence of clinical signs, symptoms or other biochemical abnormalities of renal disease. Subsequent investigations based on a high index of suspicion for exogenous substance abuse led to a novel observation of significantly raised creatinine due to the presence of boldenone, an equine anabolic steroid commonly abused in body building.
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfq663