The Dilution of Blood Plasma by Calcium-Combining Anticoagulants

When used in equimolar concentrations, five different calcium-combining anticoagulants produced uniform dilution of a given blood sample. The potassium anticoagulants seem to exert a hemolytic effect on the erythrocytes. The plasma dilution caused by a given concentration of the calcium-combining an...

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Bibliographic Details
Published in:Blood 1951-07, Vol.6 (7), p.661-664
Main Authors: Adams, Alden Ross, Mosher, William A.
Format: Article
Language:English
Subjects:
Anticoagulants
Blood Coagulation
Calcium
Humans
Old Medline
Plasma
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Summary:When used in equimolar concentrations, five different calcium-combining anticoagulants produced uniform dilution of a given blood sample. The potassium anticoagulants seem to exert a hemolytic effect on the erythrocytes. The plasma dilution caused by a given concentration of the calcium-combining anticoagulants ranged from 8 to 20 per cent in the bloods examined. This shows the importance of using serum or unoxalated plasma for comparing the plasma protein concentrations of individual blood samples.
ISSN:0006-4971
1528-0020
DOI:10.1182/blood.V6.7.661.661