Tritium Exchange from Compounds in Dilute Aqueous Solutions

ALTHOUGH considerable information is available about the lability of the tritium in tritiated compounds treated with acid or alkaline solutions 1 , little attention has been given to its lability in compounds stored in dilute aqueous solution in the essentially neutral conditions usually preferred f...

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Bibliographic Details
Published in:Nature (London) 1968-05, Vol.218 (5140), p.472-473
Main Authors: WATERFIELD, W. R, SPANNER, J. A, STANFORD, F. G
Format: Article
Language:English
Subjects:
Amino Acids - metabolism
Chromatography, Paper
Hot Temperature
Humanities and Social Sciences
letter
multidisciplinary
Science
Solutions
Tritium
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Summary:ALTHOUGH considerable information is available about the lability of the tritium in tritiated compounds treated with acid or alkaline solutions 1 , little attention has been given to its lability in compounds stored in dilute aqueous solution in the essentially neutral conditions usually preferred for biological investigations. Recently, the exchange of the C 8 proton of purine derivatives with water has been reported 2 , and we now publish some of our findings on tritium exchange in purines and in other nucleics and amino-acids, in order to make research workers using these materials more aware of this phenomenon.
ISSN:0028-0836
1476-4687
DOI:10.1038/218472a0