Candidiasis: studies pertaining to its association with endocrinopathies and pernicious anemia

Forty-four patients with chronic or recurrent candidiasis of the dermis, mucous membranes, or both, have been studied in relation to associated diseases. Thirty-one patients (Group I) had at least one associated disease. Thirteen (Group II) had only candidiasis. Neonates with oral moniliasis, childr...

Full description

Saved in:
Bibliographic Details
Published in:Pediatrics (Evanston) 1968-08, Vol.42 (2), p.231-237
Main Authors: Blizzard, R M, Gibbs, J H
Format: Article
Language:English
Subjects:
Addison Disease - complications
Adrenal Glands - immunology
Adult
Alopecia - complications
Anemia, Pernicious - complications
Candidiasis, Cutaneous - complications
Candidiasis, Cutaneous - immunology
Chronic Disease
Complement Fixation Tests
Female
Humans
Hypoparathyroidism - complications
Hypothyroidism - complications
Infant
Kidney - immunology
Liver Cirrhosis - complications
Male
Middle Aged
Mucous Membrane
Myxedema - complications
Sex Factors
Stomach - immunology
Thyroid Gland - immunology
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Forty-four patients with chronic or recurrent candidiasis of the dermis, mucous membranes, or both, have been studied in relation to associated diseases. Thirty-one patients (Group I) had at least one associated disease. Thirteen (Group II) had only candidiasis. Neonates with oral moniliasis, children with chronic debilitation, and children receiving antibiotics were eliminated from the study. Idiopathic hypoparathyroidism was the most common associated disease of the patients in Group I (26 of 31 patients). Addison's disease also was common (14 of 31 patients). Hypothyroidism, alopecia, cirrhosis, pernicious anemia, and primary gonadal failure also occurred. Evidence for subclinical disease of the thyroid, adrenal cortex, and gastric mucosa, as reflected by tissue specific antibodies, was common in patients with candidiasis. Anti-kidney antibodies also were found in 18 patients, but their significance is unclear. No etiological relationship between the candidiasis and the associated diseases could be demonstrated.
ISSN:0031-4005
1098-4275
DOI:10.1542/peds.42.2.231