Electrophysiological Correlates of Contractile Change in Mammalian and Amphibian Myocardium

Studies of canine and frog myocardium disclose a consistent inverse relation between interval-dependent contractile alterations and the duration of phase 2 of the concomitant action potentials (AP). This is true despite the differing temporal patterns of contractile change in the two species. A rela...

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Bibliographic Details
Published in:Cardiovascular research 1968-07, Vol.2 (3), p.252-260
Main Authors: Edmands, Robert E., Greenspan, Kalman, Fisch, Charles
Format: Article
Language:English
Subjects:
Action Potentials
Animals
Anura
Dogs
Electric Stimulation
Heart - physiology
Muscle Contraction - physiology
Rest
Time Factors
Ventricular Function
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Summary:Studies of canine and frog myocardium disclose a consistent inverse relation between interval-dependent contractile alterations and the duration of phase 2 of the concomitant action potentials (AP). This is true despite the differing temporal patterns of contractile change in the two species. A relation of both the inotropic state and AP configuration to K+ flux is suggested.
ISSN:0008-6363
1755-3245
DOI:10.1093/cvr/2.3.252