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Metabolism of Haemoglobin Köln, an Unstable Haemoglobin
HAEMOGLOBIN Köln (α 2 β 2 98met ) (ref. 1) is characterized by increased heat precipitability and abnormal liability to methaemoglobin and Heinz body formation in vitro 2,3 , like other unstable haemoglobins associated with hereditary Heinz body anaemias 4 . Excessive detachment of haem groups takes...
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| Published in: | Nature (London) 1968-08, Vol.219 (5153), p.494-495 |
|---|---|
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c335t-e1f49570a9df84481afec6fa30e423978f959ba776d4ace96733aa83dc18cbe23 |
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| cites | cdi_FETCH-LOGICAL-c335t-e1f49570a9df84481afec6fa30e423978f959ba776d4ace96733aa83dc18cbe23 |
| container_end_page | 495 |
| container_issue | 5153 |
| container_start_page | 494 |
| container_title | Nature (London) |
| container_volume | 219 |
| creator | KREIMER-BIRNBAUM, MARTHA PINKERTON, P. H BANNERMAN, R. M HUTCHISON, H. E |
| description | HAEMOGLOBIN Köln (α
2
β
2
98met
) (ref. 1) is characterized by increased heat precipitability and abnormal liability to methaemoglobin and Heinz body formation
in vitro
2,3
, like other unstable haemoglobins associated with hereditary Heinz body anaemias
4
. Excessive detachment of haem groups takes place
5
, and may be a source of the “dipyrrolic” urinary pigments found in this syndrome
6,7
. |
| doi_str_mv | 10.1038/219494a0 |
| format | article |
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2
β
2
98met
) (ref. 1) is characterized by increased heat precipitability and abnormal liability to methaemoglobin and Heinz body formation
in vitro
2,3
, like other unstable haemoglobins associated with hereditary Heinz body anaemias
4
. Excessive detachment of haem groups takes place
5
, and may be a source of the “dipyrrolic” urinary pigments found in this syndrome
6,7
.</description><identifier>ISSN: 0028-0836</identifier><identifier>EISSN: 1476-4687</identifier><identifier>DOI: 10.1038/219494a0</identifier><identifier>PMID: 5668432</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>Carbon Isotopes ; Erythrocytes - metabolism ; Globins - metabolism ; Glutathione - blood ; Glycine - metabolism ; Hemoglobins, Abnormal - biosynthesis ; Hemoglobins, Abnormal - metabolism ; Humanities and Social Sciences ; Humans ; letter ; Male ; Middle Aged ; multidisciplinary ; Pyrroles - urine ; Science ; Science (multidisciplinary)</subject><ispartof>Nature (London), 1968-08, Vol.219 (5153), p.494-495</ispartof><rights>Springer Nature Limited 1968</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c335t-e1f49570a9df84481afec6fa30e423978f959ba776d4ace96733aa83dc18cbe23</citedby><cites>FETCH-LOGICAL-c335t-e1f49570a9df84481afec6fa30e423978f959ba776d4ace96733aa83dc18cbe23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2727,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5668432$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>KREIMER-BIRNBAUM, MARTHA</creatorcontrib><creatorcontrib>PINKERTON, P. H</creatorcontrib><creatorcontrib>BANNERMAN, R. M</creatorcontrib><creatorcontrib>HUTCHISON, H. E</creatorcontrib><title>Metabolism of Haemoglobin Köln, an Unstable Haemoglobin</title><title>Nature (London)</title><addtitle>Nature</addtitle><addtitle>Nature</addtitle><description>HAEMOGLOBIN Köln (α
2
β
2
98met
) (ref. 1) is characterized by increased heat precipitability and abnormal liability to methaemoglobin and Heinz body formation
in vitro
2,3
, like other unstable haemoglobins associated with hereditary Heinz body anaemias
4
. Excessive detachment of haem groups takes place
5
, and may be a source of the “dipyrrolic” urinary pigments found in this syndrome
6,7
.</description><subject>Carbon Isotopes</subject><subject>Erythrocytes - metabolism</subject><subject>Globins - metabolism</subject><subject>Glutathione - blood</subject><subject>Glycine - metabolism</subject><subject>Hemoglobins, Abnormal - biosynthesis</subject><subject>Hemoglobins, Abnormal - metabolism</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>letter</subject><subject>Male</subject><subject>Middle Aged</subject><subject>multidisciplinary</subject><subject>Pyrroles - urine</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><issn>0028-0836</issn><issn>1476-4687</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1968</creationdate><recordtype>article</recordtype><recordid>eNptkM1KxDAURoMo4zgKvoDSlShYTZo0P0sZ1BFH3DjrkrY3Q4c2GZN24Yv5Ar6YldbBhau7OIcD90PolOAbgqm8TYhiimm8h6aECR4zLsU-mmKcyBhLyg_RUQgbjHFKBJugScq5ZDSZIvkCrc5dXYUmciZaaGjcunZ5ZaPnr8_aXkfaRisbeqmGv_gYHRhdBzgZ7wytHu7f5ot4-fr4NL9bxgWlaRsDMUylAmtVGsmYJNpAwY2mGFhClZBGpSrXQvCS6QIUF5RqLWlZEFnkkNAZuhi6W-_eOwht1lShgLrWFlwXMskUTRTjvXg5iIV3IXgw2dZXjfYfGcHZz0jZ70i9ejY2u7yBcieOq_T8auChJ3YNPtu4ztv-zf9a54Nrddt52LV2wjc4M3hR</recordid><startdate>19680803</startdate><enddate>19680803</enddate><creator>KREIMER-BIRNBAUM, MARTHA</creator><creator>PINKERTON, P. H</creator><creator>BANNERMAN, R. M</creator><creator>HUTCHISON, H. E</creator><general>Nature Publishing Group UK</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19680803</creationdate><title>Metabolism of Haemoglobin Köln, an Unstable Haemoglobin</title><author>KREIMER-BIRNBAUM, MARTHA ; PINKERTON, P. H ; BANNERMAN, R. M ; HUTCHISON, H. E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-e1f49570a9df84481afec6fa30e423978f959ba776d4ace96733aa83dc18cbe23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1968</creationdate><topic>Carbon Isotopes</topic><topic>Erythrocytes - metabolism</topic><topic>Globins - metabolism</topic><topic>Glutathione - blood</topic><topic>Glycine - metabolism</topic><topic>Hemoglobins, Abnormal - biosynthesis</topic><topic>Hemoglobins, Abnormal - metabolism</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>letter</topic><topic>Male</topic><topic>Middle Aged</topic><topic>multidisciplinary</topic><topic>Pyrroles - urine</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>KREIMER-BIRNBAUM, MARTHA</creatorcontrib><creatorcontrib>PINKERTON, P. H</creatorcontrib><creatorcontrib>BANNERMAN, R. M</creatorcontrib><creatorcontrib>HUTCHISON, H. E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nature (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>KREIMER-BIRNBAUM, MARTHA</au><au>PINKERTON, P. H</au><au>BANNERMAN, R. M</au><au>HUTCHISON, H. E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolism of Haemoglobin Köln, an Unstable Haemoglobin</atitle><jtitle>Nature (London)</jtitle><stitle>Nature</stitle><addtitle>Nature</addtitle><date>1968-08-03</date><risdate>1968</risdate><volume>219</volume><issue>5153</issue><spage>494</spage><epage>495</epage><pages>494-495</pages><issn>0028-0836</issn><eissn>1476-4687</eissn><abstract>HAEMOGLOBIN Köln (α
2
β
2
98met
) (ref. 1) is characterized by increased heat precipitability and abnormal liability to methaemoglobin and Heinz body formation
in vitro
2,3
, like other unstable haemoglobins associated with hereditary Heinz body anaemias
4
. Excessive detachment of haem groups takes place
5
, and may be a source of the “dipyrrolic” urinary pigments found in this syndrome
6,7
.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>5668432</pmid><doi>10.1038/219494a0</doi><tpages>2</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-0836 |
| ispartof | Nature (London), 1968-08, Vol.219 (5153), p.494-495 |
| issn | 0028-0836 1476-4687 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_84932946 |
| source | Nature Journals |
| subjects | Carbon Isotopes Erythrocytes - metabolism Globins - metabolism Glutathione - blood Glycine - metabolism Hemoglobins, Abnormal - biosynthesis Hemoglobins, Abnormal - metabolism Humanities and Social Sciences Humans letter Male Middle Aged multidisciplinary Pyrroles - urine Science Science (multidisciplinary) |
| title | Metabolism of Haemoglobin Köln, an Unstable Haemoglobin |
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