Modelling neutral lipid production by the microalga Isochrysis aff. galbana under nitrogen limitation

This article proposes a dynamical model of microalgal lipid production under nitrogen limitation. In this model, intracellular carbon is divided between a functional pool and two storage pools (sugars and neutral lipids). The various intracellular carbon flows between these pools lead to a complex d...

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Bibliographic Details
Published in:Bioresource technology 2011, Vol.102 (1), p.142-149
Main Authors: Mairet, Francis, Bernard, Olivier, Masci, Pierre, Lacour, Thomas, Sciandra, Antoine
Format: Article
Language:English
Subjects:
Biofuel
Carbohydrates - biosynthesis
Carbon
Carbon - metabolism
Cell Culture Techniques - methods
Clone Cells
Culture
Eukaryota - growth & development
Eukaryota - metabolism
Growth model
Hysteresis
Isochrysis
Lipids
Lipids - biosynthesis
Mathematical models
Models, Biological
Neutral lipid
Nitrogen - metabolism
Nitrogen starvation
Phase Transition
Phytoplankton
Pools
Predictive Value of Tests
Quotas
Reproducibility of Results
Starvation
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Summary:This article proposes a dynamical model of microalgal lipid production under nitrogen limitation. In this model, intracellular carbon is divided between a functional pool and two storage pools (sugars and neutral lipids). The various intracellular carbon flows between these pools lead to a complex dynamic with a strong discrepancy between synthesis and mobilization of neutral lipids. The model has been validated with experiments of Isochrysis aff. galbana (clone T-iso) culture under various nitrogen limitation conditions and under nitrogen starvation. The hysteresis behavior of the neutral lipid quota observed experimentally is accurately predicted.
ISSN:0960-8524
1873-2976
DOI:10.1016/j.biortech.2010.06.138