Electron‐microscopic search for virus particles in patients with leukemia and lymphoma

Material from 155 patients was examined for the presence of virus particles, especially those resembling murine leukemia particles. The thin‐section method, applied to buffy coat cells and to biopsies, proved to be the more efficient way to find particles which could be interpreted as resembling vir...

Full description

Saved in:
Bibliographic Details
Published in:Cancer 1968-11, Vol.22 (5), p.1033-1045
Main Authors: Seman, G., Seman, C.
Format: Article
Language:English
Subjects:
Biopsy
Bone Marrow - microbiology
Humans
Leukemia - blood
Leukemia - microbiology
Lymph Nodes - microbiology
Lymphoma - blood
Lymphoma - microbiology
Methods
Microscopy, Electron
Retroviridae - isolation & purification
Spleen - microbiology
Staining and Labeling
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Material from 155 patients was examined for the presence of virus particles, especially those resembling murine leukemia particles. The thin‐section method, applied to buffy coat cells and to biopsies, proved to be the more efficient way to find particles which could be interpreted as resembling viruslike particles. Examination of plasma pellets by the negative‐staining technique occasionally revealed structures resembling virus particles. However, this technique was found misleading compared with the thin‐section technique. Structures interpreted as resembling immature murine leukemia type A virus particles and in some cases mature type C particles were found in a number of patients. The possible nature of these particles is discussed.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(196811)22:5<1033::AID-CNCR2820220520>3.0.CO;2-#