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Role of Interferon in Experimental Mouse Malaria

INTERFERENCE with experimental plasmodial infections by associated infectious agents has been previously described (West Nile virus 1 ; Chlamydia psittaci , an ornithosis strain 2 ; bacterial endotoxin 3 ), but observations were not made to determine whether the effects observed were mediated by int...

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Bibliographic Details
Published in:Nature (London) 1968-11, Vol.220 (5168), p.709-710
Main Authors: SCHULTZ, WARREN W, HUANG, KUN-YEN, GORDON, FRANCIS B
Format: Article
Language:English
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Summary:INTERFERENCE with experimental plasmodial infections by associated infectious agents has been previously described (West Nile virus 1 ; Chlamydia psittaci , an ornithosis strain 2 ; bacterial endotoxin 3 ), but observations were not made to determine whether the effects observed were mediated by interferon. These reports and our own findings 4 of induction of interferon by P. berghei infection in mice led us to further investigation of mouse malaria in relation to interferon.
ISSN:0028-0836
1476-4687
DOI:10.1038/220709a0