Genetic Background of Circadian Rhythms

CIRCADIAN rhythms 1–3 have not yet been investigated in twins. The mathematical methods used in one-phase examinations of twins—variance analysis 4,5 , cross-twin analysis or intra-subject correlation—are not suitable for expressing the concordance or discordance of a certain biological phenomenon i...

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Bibliographic Details
Published in:Nature (London) 1968-12, Vol.220 (5172), p.1128-1131
Main Authors: BARCAL, R, SOVA, J, KRIZANOVSKA, M, LEVY, J, MATOUSEK, J
Format: Article
Language:English
Subjects:
Adult
Analysis of Variance
Circadian Rhythm
Computers
Female
Genetics, Medical
Histamine - blood
Humanities and Social Sciences
Humans
letter
Lipids - blood
Male
Methods
multidisciplinary
Pregnancy
Science
Science (multidisciplinary)
Serotonin - blood
Twins
Uric Acid - blood
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Summary:CIRCADIAN rhythms 1–3 have not yet been investigated in twins. The mathematical methods used in one-phase examinations of twins—variance analysis 4,5 , cross-twin analysis or intra-subject correlation—are not suitable for expressing the concordance or discordance of a certain biological phenomenon in time between the individuals of separate twin pairs. We have therefore tried to devise a method of our own, suitable both for the basal physiological research of medical genetics, and for the study of biological rhythms, for example, in human biometeorology.
ISSN:0028-0836
1476-4687
DOI:10.1038/2201128a0