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CATECHOLAMINE AND CARDIOVASCULAR RESPONSE TO ELECTRO-CONVULSION THERAPY IN MAN

Fourteen anaesthetized patients undergoing electro-convulsion therapy on one or more occasions were studied. Systolic and diastolic blood pressure, heart rate, and plasma adrenaline and noradrenaline levels were measured before, during and after the electric shock. With the electric shock, blood pre...

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Published in:British journal of anaesthesia : BJA 1965-11, Vol.37 (11), p.833-839
Main Authors: GRAVENSTEIN, J.S., ANTON, A.H., WIENER, S.M., TETLOW, A.G.
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Language:English
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container_issue 11
container_start_page 833
container_title British journal of anaesthesia : BJA
container_volume 37
creator GRAVENSTEIN, J.S.
ANTON, A.H.
WIENER, S.M.
TETLOW, A.G.
description Fourteen anaesthetized patients undergoing electro-convulsion therapy on one or more occasions were studied. Systolic and diastolic blood pressure, heart rate, and plasma adrenaline and noradrenaline levels were measured before, during and after the electric shock. With the electric shock, blood pressure and heart rate rose and adrenaline and noradrenaline levels in plasma increased steeply. These values returned to normal within 10 minutes. Asystole of about 2 seconds duration was common with application of the electric shock in patients not premedicated with atropine. With repeated electro-shocks, resting plasma noradrenaline levels decreased as did the noradrenaline response to the shock. Systolic arterial pressure was significantly correlated with circulating levels of noradrenaline in plasma.
doi_str_mv 10.1093/bja/37.11.833
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source Oxford University Press:Jisc Collections:Oxford Journal Archive: Access period 2024-2025
subjects Anesthesia, General
Blood Pressure - physiology
Depression - therapy
Electroconvulsive Therapy
Epinephrine - metabolism
Halothane - pharmacology
Heart Rate
Humans
Nitrous Oxide - pharmacology
Norepinephrine - metabolism
Thiopental - pharmacology
title CATECHOLAMINE AND CARDIOVASCULAR RESPONSE TO ELECTRO-CONVULSION THERAPY IN MAN
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