Determination of residual ethylene oxide in catheters by gas-liquid chromatography

A quantitative method for determining residual ethylene oxide in plastic and rubber catheters using gas–liquid chromatography has been developed. Tests on ethylene oxide stabilized catheters indicated that the amount of ethylene oxide in the catheters decreased as a function of aeration time up to 4...

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Bibliographic Details
Published in:Journal of biomedical materials research 1968-03, Vol.2 (1), p.165-171
Main Authors: Kulkarni, R. K., Bartak, D., Ousterhout, D. K., Leonard, Fred
Format: Article
Language:English
Subjects:
Catheterization
Chromatography
Chromatography, Gas
Ethylene Oxide - analysis
Plastics - analysis
Rubber - analysis
Sterilization
Time Factors
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Summary:A quantitative method for determining residual ethylene oxide in plastic and rubber catheters using gas–liquid chromatography has been developed. Tests on ethylene oxide stabilized catheters indicated that the amount of ethylene oxide in the catheters decreased as a function of aeration time up to 48 hr. After this period, a steady concentration of ethylene oxide in the catheters appeared to have been reached up to one week's testing.
ISSN:0021-9304
1097-4636
DOI:10.1002/jbm.820020113