Costs and adherence to antiretroviral treatment

To develop a system of data management that allows us to estimate the comparative effectiveness of the various antiretroviral treatment (ART) regimens. Retrospective observational study in patients infected with HIV with stable ART. Adherence to treatment and unit cost for each patient's treatm...

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Bibliographic Details
Published in:Farmacia hospitalaria 2010-11, Vol.34 (6), p.284-292
Main Authors: Ventura-Cerdá, J M, Ayago-Flores, D, Vicente-Escrig, E, Mollá-Cantavella, S, Alós-Almiñana, M
Format: Article
Language:Spanish
Subjects:
Adult
Anti-Retroviral Agents - economics
Anti-Retroviral Agents - therapeutic use
Costs and Cost Analysis
Female
HIV Infections - drug therapy
HIV Infections - economics
Humans
Male
Medication Adherence - statistics & numerical data
Retrospective Studies
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Summary:To develop a system of data management that allows us to estimate the comparative effectiveness of the various antiretroviral treatment (ART) regimens. Retrospective observational study in patients infected with HIV with stable ART. Adherence to treatment and unit cost for each patient's treatment was determined. The cost/patient/day was calculated and, multiplying by an adherence factor (fADH), the (cost/patient/day)(ADH). The comparison of both allowed us to obtain the Δcost/patient, which estimates the additional costs caused by lack of adherence. The incremental cost-effectiveness (iCER), grouping the results by the various coformulated drugs ("combos"). A study of the budgetary impact of these combos was carried out. 468 patients were evaluated (62% adherent). Average adherence was 88±18%. The average value of (cost/patient/day) (ADH) was significantly higher than the cost/patient/day (27.3±9.8€ compared to 24.3±7.6€. p
ISSN:1130-6343
DOI:10.1016/j.farma.2010.01.016