Ultrastructure of a hemangiopericytoma and a glomus tumor

A comparative ultrastructural study of a case of hemangiopericytoma and one of glomus tumor is presented. The study revealed the hemangiopericytoma cells to be large with large irregular nuclei. The intercellular spaces are filled with light osmiophilic material resembling basement membrane. In the...

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Bibliographic Details
Published in:Cancer 1968-11, Vol.22 (6), p.1239-1249
Main Authors: Murad, Tariq M., Haam, Emmerich Von, Narasimha, M. S. Murthy
Format: Article
Language:English
Subjects:
Adult
Cytoplasm
Diagnosis, Differential
Female
Fingers
Glomus Tumor - pathology
Head and Neck Neoplasms - pathology
Hemangiopericytoma - pathology
Humans
Male
Mitochondria, Muscle
Muscle, Smooth - pathology
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Summary:A comparative ultrastructural study of a case of hemangiopericytoma and one of glomus tumor is presented. The study revealed the hemangiopericytoma cells to be large with large irregular nuclei. The intercellular spaces are filled with light osmiophilic material resembling basement membrane. In the glomus tumor, two types of cells are identified. The more frequent cells are epithelioid smooth muscle cells with large ovoid nuclei and cytoplasm filled with fine filaments. The second type of cell is less frequent and is recognized as a mast cell. It is suggested that the release of mast cell granules plays an important role in the contraction of epithelioid smooth muscle and therefore controls the flow of blood in the glomus structure.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(196811)22:6<1239::AID-CNCR2820220622>3.0.CO;2-2