Comparison the effects of metoclopramide and dropridol associated with dexamethasone on post operative nausea and vomiting

The aim of study was, comparison of effects of Metoclopramide and Dropridol associated with Dexamethasone on prevalence of nausea and vomiting after operation was considered. In this study 160 patients ASA physical status I were divided into two groups. In both groups, premedication and induction of...

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Bibliographic Details
Published in:Pakistan journal of biological sciences 2010-12, Vol.13 (24), p.1219-1222
Main Authors: Yousef, M, Ebrahim, N, Ebrahim, A, Hosssain, B
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Antiemetics - administration & dosage
Antiemetics - therapeutic use
Dexamethasone - administration & dosage
Dexamethasone - therapeutic use
Droperidol - administration & dosage
Droperidol - therapeutic use
Female
Humans
Male
Metoclopramide - administration & dosage
Metoclopramide - therapeutic use
Middle Aged
Postoperative Nausea and Vomiting - prevention & control
Vomiting - prevention & control
Young Adult
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Summary:The aim of study was, comparison of effects of Metoclopramide and Dropridol associated with Dexamethasone on prevalence of nausea and vomiting after operation was considered. In this study 160 patients ASA physical status I were divided into two groups. In both groups, premedication and induction of anesthesia were given equally according to weight. To the first group, Metoclopramide associated with Dexamethasone and to the second group, Dropridol associated with Dexamethasone was ordered. At the end of the operation, after removing tracheal tube, prevalence of nausea and vomiting in both groups was considered after 2 h and results were analyzed with t-test and Chi-square. Ratio of nausea and vomiting after operation in the first group was 24% and in the second 8%. So results show that prevalence of nausea and vomiting in the second group was considerably lower than the first group (p < 0.004). According to the results of this study our conclusion, Dropridol with dexamethasone given at the before of general anesthesia was more effective in decreasing the prevalence of nausea and vomiting in patients compared with metoclopramide with dexamethasone.
ISSN:1028-8880
DOI:10.3923/pjbs.2010.1219.1222