Vitamin D Deficiency in Children with Inflammatory Bowel Disease

Background Osteopenia and osteoporosis are commonly seen in inflammatory bowel disease (IBD). Vitamin D deficiency potentially contributes to diminished bone acquisition in childhood. Objectives The objectives of this study were to assess vitamin D in a group of Australian children with IBD and to a...

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Bibliographic Details
Published in:Digestive diseases and sciences 2011-03, Vol.56 (3), p.830-836
Main Authors: Levin, Alon D, Wadhera, Veena, Leach, Steven T, Woodhead, Helen J, Lemberg, Daniel A, Czarina Mendoza-Cruz, A, Day, Andrew S
Format: Article
Language:English
Subjects:
Adolescent
Alfacalcidol
Australia - epidemiology
Biochemistry
Biological and medical sciences
Bones, joints and connective tissue. Antiinflammatory agents
Calcifediol
Child
Children's furniture
Cohort Studies
Corticosteroids
Enteral Nutrition
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Gastroenterology
Gastroenterology. Liver. Pancreas. Abdomen
Gastrointestinal diseases
Hepatology
Humans
Inflammatory bowel disease
Inflammatory Bowel Diseases - blood
Inflammatory Bowel Diseases - complications
Inflammatory Bowel Diseases - drug therapy
Inflammatory Bowel Diseases - epidemiology
Male
Medical sciences
Medicine
Medicine & Public Health
Oncology
Original Article
Osteoporosis
Other diseases. Semiology
Pharmacology. Drug treatments
Prevalence
Retrospective Studies
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Transplant Surgery
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Vitamin D
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D deficiency
Vitamin D Deficiency - blood
Vitamin D Deficiency - epidemiology
Vitamin D Deficiency - etiology
Vitamin D Deficiency - prevention & control
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Summary:Background Osteopenia and osteoporosis are commonly seen in inflammatory bowel disease (IBD). Vitamin D deficiency potentially contributes to diminished bone acquisition in childhood. Objectives The objectives of this study were to assess vitamin D in a group of Australian children with IBD and to ascertain associations between vitamin D status and key clinical factors, for example disease location and severity. Methods Data were obtained retrospectively from the records of children with IBD who had at least one measurement of serum 25-hydroxyvitamin D (25(OH)D) over a two-year period. Demographic variables, disease activity, inflammatory markers, disease location, duration, and therapy were recorded. Moderate and severe deficiency were defined as 25(OH)D
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-010-1544-3