Pathological changes caused by Anoplocephala perfoliata in the mucosa/submucosa and in the enteric nervous system of equine ileocecal junction

In this study, pathological changes caused by Anoplocephala perfoliata in the ileocecal junction were investigated in 31 regularly slaughtered mixed-breed horses of both sexes. Our results showed a significant relationship between parasite burden and grading of histopathological lesions in the mucos...

Full description

Saved in:
Bibliographic Details
Published in:Veterinary parasitology 2011-02, Vol.176 (1), p.43-52
Main Authors: Pavone, Silvia, Veronesi, Fabrizia, Genchi, Claudio, Fioretti, Daniela Piergili, Brianti, Emanuele, Mandara, Maria Teresa
Format: Article
Language:English
Subjects:
Animals
Anoplocephala perfoliata infection
Cecum - innervation
Cecum - pathology
Cestoda - classification
Cestode Infections - pathology
Cestode Infections - veterinary
Enteric nervous system
Female
Horse
Horse Diseases - parasitology
Horse Diseases - pathology
Horses
Ileocecal junction
Ileum - innervation
Ileum - pathology
Intestinal Mucosa - pathology
Male
Pathological changes
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:In this study, pathological changes caused by Anoplocephala perfoliata in the ileocecal junction were investigated in 31 regularly slaughtered mixed-breed horses of both sexes. Our results showed a significant relationship between parasite burden and grading of histopathological lesions in the mucosa and submucosa. Hypertrophy of the circular muscle layer was found in infected horses. Moreover, enteric nervous system evaluation showed a significant injury of intestinal nervous elements in the horses with moderate to high parasitism expressed as an increase of degenerative-regressive changes in neuronal cells and a decrease in the number of myenteric ganglia and neuronal cells. These findings can help to clarify the pathogenesis of intestinal motility disorders associated with A. perfoliata infection in horses.
ISSN:0304-4017
1873-2550
DOI:10.1016/j.vetpar.2010.10.041