Assessment of malignant potential of small hypervascular hepatocellular carcinoma using B-mode ultrasonography

Aim:  Evaluation of malignant potential is important to determine the treatment strategy for small hepatocellular carcinoma (HCC). The aim of the present study was to establish a method of assessing the malignant potential of small hypervascular HCC using B‐mode ultrasonography. Methods:  One hundre...

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Published in:Hepatology research 2011-03, Vol.41 (3), p.233-239
Main Authors: Moribata, Kosaku, Tamai, Hideyuki, Shingaki, Naoki, Mori, Yoshiyuki, Enomoto, Shotaro, Shiraki, Tatsuya, Deguchi, Hisanobu, Ueda, Kazuki, Inoue, Izumi, Maekita, Takao, Iguchi, Mikitaka, Yanaoka, Kimihiko, Oka, Masashi, Ichinose, Masao
Format: Article
Language:English
Subjects:
carcinoma
hepatocellular
ultrasonography
α-fetoproteins
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Summary:Aim:  Evaluation of malignant potential is important to determine the treatment strategy for small hepatocellular carcinoma (HCC). The aim of the present study was to establish a method of assessing the malignant potential of small hypervascular HCC using B‐mode ultrasonography. Methods:  One hundred and thirteen arterial hypervascular HCC nodules under 3 cm diagnosed by biopsy or surgical resection (20.5 ± 6.3 mm) were classified into two groups ultrasonographically: type 1 with (n = 27) and type 2 without (n = 86) a halo. Type 2 was categorized into three subgroups: type 2a, homogenous hyperechoic (n = 9); type 2b, hypoechoic with a smooth margin (n = 35); and type 2c, hypoechoic with an irregular or unclear margin (n = 42). Results:  The mean diameter of type 2a nodules was significantly smaller than that of other HCC types (P 
ISSN:1386-6346
1872-034X
DOI:10.1111/j.1872-034X.2010.00763.x