Sutureless tympanoplasty using acellular dermis

Abstract Objective A prospective randomized unblinded controlled trial was conducted by comparing acellular dermis with temporalis fascia as graft materials in tympanoplasty (type 1) in terms of operative time, postoperative pain, graft success rate, and audiologic outcome. Study design Forty-two pa...

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Bibliographic Details
Published in:American journal of otolaryngology 2011-03, Vol.32 (2), p.96-99
Main Authors: Raj, Anoop, MBBS, MS, Sayal, Ankush, MBBS, MS, Rathore, P.K., MBBS, MS, Meher, Ravi, MBBS, MS, DNB
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Dermis - cytology
Dermis - transplantation
Fascia - transplantation
Graft Rejection
Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics
Hearing - physiology
Humans
Medical sciences
Middle Aged
Otitis Media, Suppurative - surgery
Otolaryngology
Otorhinolaryngology. Stomatology
Pain, Postoperative - prevention & control
Prospective Studies
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the ear, the auditive nerve and the facial nerve
Sutures
Temporal Muscle
Time Factors
Treatment Outcome
Tympanic Membrane Perforation - surgery
Tympanoplasty - methods
Young Adult
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Summary:Abstract Objective A prospective randomized unblinded controlled trial was conducted by comparing acellular dermis with temporalis fascia as graft materials in tympanoplasty (type 1) in terms of operative time, postoperative pain, graft success rate, and audiologic outcome. Study design Forty-two patients with (inactive) chronic suppurative otitis media of tubotympanic type were randomized, matched, and divided equally into 2 groups of 21 each. One group underwent tympanoplasty (type 1) via transcanal route using temporalis fascia graft and the other using acellular dermis. Both groups were compared for operative time, postoperative pain, graft success rate, and audiologic improvement in hearing. Results There was a statistically significant reduction in operative time ( P < .05) and postoperative pain ( P < .05) in the acellular dermis group. However, there was no statistical difference in graft success rate ( P > .05) and hearing improvement ( P > .05) between both the groups. Conclusion Results of tympanoplasty using acellular dermis as graft material are comparable to that using temporalis fascia in terms of graft uptake and hearing improvement. However, tympanoplasty using acellular dermis has the advantage of shorter operative time and lesser postoperative pain.
ISSN:0196-0709
1532-818X
DOI:10.1016/j.amjoto.2009.10.007