Shortening the 4-Hour Gastric-Emptying Protocol

• Published in: Clinical nuclear medicine 2011-04, Vol.36 (4), p.283-285
• Main Authors: Bonta, Dacian V, Lee, Ho Y, Ziessman, Harvey A
• Format: Article
• Language: English
• Subjects: Diagnostic Techniques, Digestive System - standards; Feasibility Studies; Female; Gastric Emptying; Humans; Likelihood Functions; Male; Reference Values; Reproducibility of Results; Time Factors
• ISSN: 0363-9762; 1536-0229
• DOI: 10.1097/RLU.0b013e31820aa091

PURPOSE:A standardized 4-hour gastric-emptying protocol has been recommended by a consensus panel. However, a study length of 4 hours may be inconvenient. The purpose of this investigation was to determine if the percent emptying at 2 hours could predict abnormal or normal results at 4 hours. METHODS:Our data consist of 2 distinct patient groups, containing 174 and 158 patients, respectively. All patients were given a standardized meal according to the Tougas et al protocol. Percent gastric emptying was measured at 1, 2, 3, and 4 hours (or until gastric emptying was equal to or more than 90%). The sensitivity, specificity, and the likelihood ratios of the 2-hour cutoffs were determined using the 4-hour data as the standard. We have estimated the accuracy and percent of studies stopped at 2 hours, resulting from various “definitely normal” and “definitely abnormal” threshold combinations. RESULTS:Using gastric emptying of less than 35% at 2 hours for diagnosis of delayed gastric emptying, and emptying at 2 hours greater than 55% for a diagnosis of normal gastric emptying yielded accuracies of 0.966 and 0.949 in the 2 datasets, respectively, compared with the Tougas standard values. The observed 2-hour gastric-emptying values would have allowed early termination in 79% and 78% of the studies, respectively. CONCLUSION:Adopting criteria for the termination of gastric-emptying study at 2 hours in selected patients yields significant reductions in the average length of a gastric-emptying study, while maintaining study accuracy.