Local recurrence after partial mastectomy: Relation to initial surgical margins

Abstract Background Local recurrence (LR) after partial mastectomy (PM) has been associated with inadequate surgical margins. We assessed LR association with initial margins after PM in patients receiving postoperative radiation therapy (RT). Methods Initial margins, re-excision status, and ipsilate...

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Bibliographic Details
Published in:The American journal of surgery 2011-03, Vol.201 (3), p.374-378
Main Authors: McCahill, Laurence E., M.D, Single, Richard, Ph.D, Ratliff, John, J.D, Sheehey-Jones, Johanna, R.N., B.S.N, Gray, Ann, James, Ted, M.D
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Breast cancer
Breast Neoplasms - pathology
Breast Neoplasms - radiotherapy
Breast Neoplasms - surgery
Cancer surgery
Cancer surgery quality
Cancer therapies
Carcinoma, Ductal, Breast - pathology
Carcinoma, Ductal, Breast - surgery
Carcinoma, Intraductal, Noninfiltrating - pathology
Carcinoma, Intraductal, Noninfiltrating - surgery
Carcinoma, Lobular - pathology
Carcinoma, Lobular - surgery
Confounding Factors (Epidemiology)
Female
General aspects
Gynecology. Andrology. Obstetrics
Histology
Hospitals
Humans
Mammary gland diseases
Mastectomy
Mastectomy, Segmental
Medical sciences
Middle Aged
Neoplasm Recurrence, Local - prevention & control
Outcomes
Patients
Radiation
Radiation therapy
Radiotherapy, Adjuvant
Reoperation
Studies
Surgeons
Surgery
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the genital tract and mammary gland
Surgical outcomes
Treatment Outcome
Tumors
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Description
Summary:Abstract Background Local recurrence (LR) after partial mastectomy (PM) has been associated with inadequate surgical margins. We assessed LR association with initial margins after PM in patients receiving postoperative radiation therapy (RT). Methods Initial margins, re-excision status, and ipsilateral LR were identified for all patients having initial PM from 2003 to 2008. Results Seven hundred twelve patients underwent PM as their final procedure, and 598 (84.0%) had adjuvant RT. Initial margins were positive or
ISSN:0002-9610
1879-1883
DOI:10.1016/j.amjsurg.2010.09.024