F-18 FDG PET/CT Detecting Thyroid Plasmacytoma After the Successful Treatment of Gastric Large B-Cell Lymphoma

Thyroid plasmacytoma is a rare form of extramedullary plasmacytoma. We describe an 82-year-old man with gastric large B-cell lymphoma who had complete response after receiving chemotherapy and rituximab, an anti-CD20 chimeric monoclonal antibody. Thyroid uptake was seen on follow-up F-18 fluorodeoxy...

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Bibliographic Details
Published in:Clinical nuclear medicine 2011-04, Vol.36 (4), p.317-319
Main Authors: Shahani, Sadeka, Ahmad, Anbar, Barakat, Fareed H, Chuang, Hubert H, Fowler, Nathan H, Myers, Jeffrey N, Stava, Charles, Habra, Mouhammed Amir
Format: Article
Language:English
Subjects:
Aged, 80 and over
False Positive Reactions
Fluorodeoxyglucose F18
Humans
Lymphoma, B-Cell - drug therapy
Lymphoma, B-Cell - therapy
Male
Plasmacytoma - diagnosis
Plasmacytoma - diagnostic imaging
Positron-Emission Tomography
Stomach Neoplasms - drug therapy
Stomach Neoplasms - therapy
Thyroid Neoplasms - diagnosis
Thyroid Neoplasms - diagnostic imaging
Tomography, X-Ray Computed
Treatment Outcome
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Summary:Thyroid plasmacytoma is a rare form of extramedullary plasmacytoma. We describe an 82-year-old man with gastric large B-cell lymphoma who had complete response after receiving chemotherapy and rituximab, an anti-CD20 chimeric monoclonal antibody. Thyroid uptake was seen on follow-up F-18 fluorodeoxyglucose-positron emission tomography/computerized tomography scan (FDG PET/CT) imaging. The left thyroid lobe uptake proved to be plasmacytic neoplasm, whereas the right lobe uptake represented thyroiditis. FDG PET scan is a useful tool for monitoring disease activity in lymphoma patients; however, other benign processes could lead to false positive findings.
ISSN:0363-9762
1536-0229
DOI:10.1097/RLU.0b013e31820aa079