Age vs Alzheimer's: A computational model of changes in representation

• Published in: Brain and cognition 2001-06, Vol.46 (1), p.86-90
• Main Authors: Conley, Patrick, Burgess, Curt, Glosser, Guila
• Format: Article
• Language: English
• Subjects: Age Factors; Aged; Aging - physiology; Alzheimer Disease; Humans; Language Disorders - diagnosis; Memory Disorders - diagnosis; Middle Aged; Psychological Theory; Semantics
• ISSN: 0278-2626; 1090-2147
• DOI: 10.1016/S0278-2626(01)80040-3

Previous research has demonstrated that the language of older adults leads to denser representations in a high dimensional model of memory than does the language of younger adults (Conley & Burgess, in press), and thus that density in the model (HAL or the hyperspace analogue to language) may constitute a useful metric in comparing memory for younger and older adults. This paper extends the previous research by examining the role of density in semantic representations that emerged from the language generated by adults with Alzheimer's and comparing the results with age-matched normal controls. We found that, just as older adults have denser representations in semantic space than do younger adults, adults with Alzheimer's have still denser representations than normal older adults. These results support the hypothesis that greater density, normally associated in the model with good semantic depth, may in fact reach a “saturation point” and affect retrieval in older adults and especially adults with Alzheimer's.